Evidence map›Paper›PMID 34244963›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2021

Dental enamel defects and oral cavity manifestations in Asian patients with celiac disease.

Anam Ahmed, Alka Singh, Smile Kajal, Ashish Chauhan, Mahendra S Rajput, Vikas Banyal, Vineet Ahuja, Govind K Makharia

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Dental Manifestations and Celiac Disease-An Overview.Journal of clinical medicine · 2023
    Review
  12. Editorial commentary on Indian Journal of Gastroenterology-July-August 2021.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anam AhmedDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Alka SinghDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Smile KajalDepartment of Otorhinolaryngology and Head - Neck Surgery, All India Institute of Medical Sciences, New Delhi 110 029, India.
Ashish ChauhanDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Mahendra S RajputDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Vikas BanyalDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Vineet AhujaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.
Govind K MakhariaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India. govindmakharia@gmail.com.ORCID http://orcid.org/0000-0002-2474-2194
All India Institute of Medical Sciences · IN

Funding

Department of Biotechnology, Government of India Ref No - IEC-324/01.07.2016
6 · The paper itself

Abstract

backgroundWhile the small intestine is the main site of disease, many other organs are affected by celiac disease (CeD). Dental enamel defects (DED) are common in patients with CeD, and these are one of the indicators of CeD, even when no other symptom of CeD is present. Data on dental and oral cavity manifestations in Asian patients with CeD are scanty. The purpose of the current study was to evaluate dental and oral manifestations in Asian patients with CeD.

methodsWe recruited 118 patients with biopsy-confirmed CeD (36 treatment naïve and 82 on follow-up for at least 1 year on gluten-free diet [GFD]) and 40 controls. Diagnosis was made as per the standard criteria. Oral and dental manifestations were evaluated by a dental surgeon. The DED were evaluated according to Aine's criteria.

resultsOverall higher number of patients with CeD (66.9%), both treatment naïve (69.4%) and those on GFD (65.8%) had DED in comparison to controls (20%) (odds ratio, 8.1, 95% confidence interval [CI] 3.4-19.2; p<0.001). Specific/bilaterally symmetrical DED were significantly higher in patients with CeD than controls. Recurrent aphthous ulcers were also significantly higher in patients with CeD. Approximately 80.6% and 63.4% treatment-naïve patients and those on GFD, respectively reported dry mouth sensation, which was significantly higher than the controls.

conclusionAlmost two-third of patients with CeD had DED. Physicians and dietitians caring for patients with CeD should be trained in identification of DED and other oral manifestations of CeD.

Indexed as

Dental EnamelAdultAsian PeopleCase-Control StudiesCeliac DiseaseDiet, Gluten-FreeFemaleHumansMaleMouth DiseasesPrevalenceStomatitis, AphthousTooth AbnormalitiesTooth DiseasesUlcerXerostomiaAnti-tissue-transglutaminase antibodyCariesCheilosisDry mouthEnteropathyGlutenMineralizationRecurrent aphthous ulcersTeethXerostomia

Identifiers

PMID34244963
OpenAlexW3177877627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.