ArticleCancer causes & control : CCC2021
Prostate cancer survival in sub-Saharan Africa by age, stage at diagnosis, and human development index: a population-based registry study.
Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06630962 (Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prostate cancer screening and associated factors in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2026Pooled it
- Burden, clinical characteristics, and management patterns of prostate cancer in Nigeria: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Epidemiology of prostate cancer in Nigeria: a mixed methods systematic review.Cancer causes & control : CCC · 2025Pooled it
- Trial
- Clinicopathological Profile of Prostate Cancer Patients at a Tertiary Hospital in the Eastern Cape, South Africa.International journal of environmental research and public health · 2026Article
- A global review and perspective on prostate cancer survival: findings from survival studies of cancer registration data.Journal of the National Cancer Center · 2026Article
- Factors Associated With Risk Stratification and Overall Survival of Black South African Men With Non-Metastatic Prostate Cancer.Cancer medicine · 2026Article
- Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN.Research square · 2026Article
- Assessing the Level of Prostate Cancer Care in a Low-Resource Setting: Disease Pattern, Current Situation of Care, and the Need for Reform-A Retrospective Observational Study From East Oncology Centre, Sudan.Advances in urology · 2026Article
- Unravelling prostate cancer risk and protective factors among urology patients in a Tanzanian population.Frontiers in oncology · 2026Article
- Recent Patterns and Trends in Global Prostate Cancer Incidence and Mortality: An Update.European urology · 2025Article
- Quality of Care and Survival Outcomes Among Patients With Clinically Localized Prostate Cancer in Nigeria.JCO global oncology · 2025Article
- The Role of Immunohistochemistry for AMACR/p504s and p63 in Distinguishing Prostate Cancer from Benign Prostate Tissue Samples in Botswana.Research and reports in urology · 2025Article
- Predictors of late diagnosis of prostate cancer among men of African ancestry receiving care at urology clinic, Federal Medical Centre, Abeokuta.Ecancermedicalscience · 2025Article
- Article
- Article
- Cancer survival in sub-Saharan Africa (SURVCAN-3): a population-based study.The Lancet. Global health · 2024Article
- Moving forward through consensus: a national Delphi approach to determine the top research priorities in prostate cancer in Uganda.BMJ open · 2023Article
- Burden of prostate cancer and relationship with the human development index (HDI) in Asia: A study of Global Burden disease in 2019.Caspian journal of internal medicine · 2023Article
- Advancing oncology drug therapies for sub-Saharan Africa.PLOS global public health · 2023Review
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
objectivesTo estimate observed and relative survival of prostate cancer patients in sub-Saharan Africa (SSA) and to examine the influence of age, stage at diagnosis and the Human Development Index (HDI). PATIENTS AND
methodsIn this comparative registry study, we selected a random sample of 1752 incident cases of malign prostatic neoplasm from 12 population-based cancer registries from 10 SSA countries, registered between 2005 and 2015. We analyzed the data using Kaplan-Meier and Ederer II methods to obtain outcome estimates and flexible Poisson regression modeling to calculate the excess hazards of death
resultsFor the 1406 patients included in the survival analyses, 763 deaths occurred during 3614 person-years of observation. Of patients with known stage, 45.2% had stage IV disease, 31.2% stage III and only 23.6% stage I and II. The 1 and 5-year relative survival for the entire cohort was 78.0% (75.4-80.7) and 60.0% (55.7-64.6), while varying between the registries. Late presentation was associated with increased excess hazards and a 0.1 increase in the HDI was associated with a 20% lower excess hazard of death, while for age at diagnosis no association was found.
conclusionsWe found poor survival of SSA prostatic tumor patients, as well as high proportions of late stage presentation, which are associated with inferior outcome. This calls for investment in health-care systems and action regarding projects to raise awareness among the population to achieve earlier diagnosis and improve survival.
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