ArticleClinical and experimental nephrology2021
The association between frailty and chronic kidney disease; cross-sectional analysis of the Nambu Cohort Study.
Article in Clinical and experimental nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence and influencing factors of frailty in patients with chronic kidney disease: a systematic review and meta-analysis.International urology and nephrology · 2024Pooled it
- Association between glomerular filtration rate and comprehensive geriatric assessment parameters in older adults.International urology and nephrology · 2026Article
- Baseline Characteristics of Frailty and Disease Stage in Older People Living With CKD.Kidney international reports · 2025Article
- Relationship between Frailty Assessed Using the Kihon Checklist and Rheumatoid Arthritis.Progress in rehabilitation medicine · 2025Article
- A Pilot Study on Circulating, Cellular, and Tissue Biomarkers in Osteosarcopenic Patients.International journal of molecular sciences · 2024Article
- Anemia and frailty in the aging population: implications of dietary fiber intake (findings of the US NHANES from 2007-2018).BMC geriatrics · 2023Article
- Association between sarcopenia and frailty in elderly patients with chronic kidney disease.Journal of cachexia, sarcopenia and muscle · 2023Article
- Use of frailty assessment instruments in nephrology populations: a scoping review.BMC geriatrics · 2023Article
- Relationship of Frailty with Kidney Function in Adults More Than 60-Years-Old: Effect of Using Different Formulas to Estimate Glomerular Filtration Rate.Clinical interventions in aging · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth frailty and chronic kidney disease (CKD) increase with age and share many similarities. Many studies have demonstrated an association between frailty and chronic kidney disease (CKD), but an association with dipstick proteinuria is limited.
methodsThis is the cross-sectional analysis of the Nambu Cohort Study at the beginning of observation. Frailty was diagnosed using Kihon Checklist. Logistic analysis was used to evaluate the association between frailty and CKD or dipstick proteinuria.
resultsAmong a total of 630 outpatients [age, 78 (70-84) years, men, 50%], the prevalence of patients with pre-frailty and frailty was 32% and 40%, respectively. The proportion of patients with pre-frailty and frailty increased with decreasing estimated glomerular filtration rate (eGFR) and increasing dipstick proteinuria levels. The odds ratios (95% confidence intervals) for CKD stage of 60 < eGFR ≤ 45 ml/min/1.73 m
conclusionElderly patients with CKD had a higher prevalence of pre-frailty and frailty. By adding urinary protein information to eGFR, the link between CKD and frailty becomes even more robust.
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