Evidence map›Paper›PMID 34244871›Full record

ArticleAIDS and behavior2021

The Role of Alcohol-Related Behavioral Risk in the Design of HIV Prevention Interventions in the Era of Antiretrovirals: Alcohol Challenge Studies and Research Agenda.

William H George, Jessica A Blayney, Cynthia A Stappenbeck, Kelly Cue Davis

Abstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William H GeorgeDepartment of Psychology, University of Washington, Box 351525, Seattle, WA, 98195-1525, USA. bgeorge@uw.edu.ORCID http://orcid.org/0000-0002-4426-3166
Jessica A BlayneyDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Cynthia A StappenbeckDepartment of Psychology, Center for Research on Interpersonal Violence, Georgia State University, Atlanta, GA, USA.
Kelly Cue DavisEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ, USA.

Funding

Women's HIV Risk: Alcohol Intoxication, Victimization History & Partner FactorsR01AA016281 · NIAAA · UNIVERSITY OF WASHINGTON · PI DAVIS, KELLY CUE, GEORGE, WILLIAM H · 2007 to 2016
$5.0M
Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional FactorsR37AA025212 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Kelly Cue Davis · 2018 to 2026
$3.8M
Web-Based Treatment of Heavy Drinking Among Women with a History of Sexual TraumaK08AA021745 · NIAAA · UNIVERSITY OF WASHINGTON · PI STAPPENBECK, CYNTHIA A. · 2014 to 2018
$852k
Technology-based intervention for alcohol-related sexual risk behaviors in young women with sexual victimization historiesR00AA028777 · NIAAA · UNIVERSITY OF WASHINGTON · PI BLAYNEY, JESSICA ALLISON · 2023 to 2025
$741k
Technology-based intervention for alcohol-related sexual risk behaviors in young women with sexual victimization historiesK99AA028777 · NIAAA · UNIVERSITY OF WASHINGTON · PI BLAYNEY, JESSICA ALLISON · 2021 to 2022
$301k
NIAAA NIH HHS 2R37AA025212NIAAA NIH HHS K08 AA021745NIAAA NIH HHS K08AA021745NIAAA NIH HHS K99 AA028777NIAAA NIH HHS K99AA028777NIAAA NIH HHS R00 AA028777NIAAA NIH HHS R01 AA016281NIAAA NIH HHS R01AA016281NIAAA NIH HHS R37 AA025212
6 · The paper itself

Abstract

HIV/AIDS remains a significant health threat and alcohol is a robust contributing factor. After 25 years of alcohol challenge studies investigating alcohol-related behavioral risk (ARBR), much has been learned delineating how drinking influences sexual transmission. We examine this research and consider its relevance for interventions in the era of antiretrovirals. We consider prototypic alcohol challenge methods, illustrative findings, and prevention/intervention implications, noting three perspectives: (a) scale up/extend existing interventions, including identifying under-targeted risk groups and intersecting with PrEP/PEP interventions; (b) modify existing interventions by cultivating psychoeducational content related to alcohol expectancies, alcohol myopia, sexual arousal, risk perception, sexual abdication, and condom use resistance; and (c) innovate new interventions through Science of Behavior Change approaches and repurposing ARBR paradigms. Finally, we suggest research directions concluding that until HIV incidence diminishes significantly, psychosocial interventions addressing the nexus of alcohol use, sexual transmission, and adherence to biomedical protocols will be an important priority.

Indexed as

Acquired Immunodeficiency SyndromeAlcohol DrinkingHIV InfectionsRisk-TakingAnti-Retroviral AgentsHumansSafe SexSexual BehaviorAnti-Retroviral AgentsAlcoholAlcohol challengeHIV riskIntervention implicationsSexual risk

Identifiers

PMID34244871
PMCPMC8846420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.