Evidence map›Paper›PMID 34244859›Full record

ArticleAmino acids2021

Cortisol enhances citrulline synthesis from proline in enterocytes of suckling piglets.

E Lichar Dillon, Guoyao Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Muscle protein catabolism and splanchnic arginine consumption drive arginine dysregulation duringAmerican journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  4. Metabolism and Nutrition of L-Glutamate and L-Glutamine in Ruminants.Animals : an open access journal from MDPI · 2024
    Review
  5. Characteristics of Nutrition and Metabolism in Dogs and Cats.Advances in experimental medicine and biology · 2024
    Article
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  8. Article
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  10. Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

E Lichar DillonDepartment of Animal Science and Faculty of Nutrition, Texas A&M University, College Station, TX, 77843-2471, USA.
Guoyao WuDepartment of Animal Science and Faculty of Nutrition, Texas A&M University, College Station, TX, 77843-2471, USA. g-wu@tamu.edu.ORCID http://orcid.org/0000-0001-8058-6969
Texas A&M University · US

Funding

Texas A&M AgriLife Research H8200
6 · The paper itself

Abstract

There are marked decreases in plasma concentrations of cortisol and arginine (an essential amino acid for neonates) as well as intestinal citrulline synthesis in piglets during the first 14 days of life. The objective of this study was to test the hypothesis that increasing plasma cortisol concentrations by cortisol administration may prevent the decline in intestinal citrulline and arginine synthesis from proline, thereby possibly increasing plasma arginine concentration in suckling piglets and their growth. Seven-day-old pigs reared by sows received daily intramuscular injections of hydrocortisone 21-acetate (25 mg/kg) or vehicle solution (saline) (n = 10/group). At 14 days of age, piglets were used to prepare jejunal enterocytes. Cells were incubated at 37 °C for 30 min in oxygenated Krebs buffer containing 5 mM glucose, 2 mM [U-

Indexed as

AnimalsAnimals, SucklingArginineCell ProliferationCitrullineEnterocytesGlutamineHydrocortisoneIleumJejunumMaleProlineProline OxidaseProtein BiosynthesisSwineArginineCitrullineGlutamineHydrocortisoneProlineProline OxidaseAmino acidsDevelopmentGlucocorticoidsMetabolismSmall intestine

Identifiers

PMID34244859
OpenAlexW3182163692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.