Evidence map›Paper›PMID 34244850›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2022

Trapeziectomy versus joint replacement for first carpometacarpal (CMC 1) joint osteoarthritis: a systematic review and meta-analysis.

Siddarth Raj, Reece Clay, Saajan Ramji, Raghav Shaunak, Arshan Dadrewalla, Vikram Sinha, Shalin Shaunak

2 registry-linked trialsOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05644132 nacompletednot on this map

Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial

TypeinterventionalSponsorLoci OrthopaedicsRan2021 to 2024Enrolled15ConditionsOsteoarthritis Thumb Base JointArmsInDx Implant for the carpometacarpal joint
NCT06467669 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Predictive Outcomes for Selective Thumb Carpometacarpal Joint Denervation

TypeinterventionalSponsorUniversity of CalgaryRan2024 to 2026Enrolled60ConditionsCMC ArthritisArmsWrist denervation procedure
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Total Trapeziometacarpal Joint Arthroplasty Using the Uncemented HORUSJournal of functional morphology and kinesiology · 2026
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  13. [Current Trends in the Implantation of the Touch Prosthesis at the Thumb Carpometacarpal Joint: Results of the 1st German-Speaking User Meeting].Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 2024
    Article
  14. Review
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  17. Readmission and Reoperation Following Carpometacarpal Arthroplasty.Journal of hand surgery global online · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Siddarth RajKing's College London, GKT School of Medicine, London, UK. Siddarth.raj@kcl.ac.uk.ORCID http://orcid.org/0000-0002-6341-6615
Reece ClayKing's College London, GKT School of Medicine, London, UK.
Saajan RamjiKing's College London, GKT School of Medicine, London, UK.
Raghav ShaunakKing's College London, GKT School of Medicine, London, UK.
Arshan DadrewallaKing's College London, GKT School of Medicine, London, UK.
Vikram SinhaKing's College London, GKT School of Medicine, London, UK.
Shalin ShaunakDepartment of Trauma and Orthopaedic Surgery, NHS KSS Deanery, London, UK.
King's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis directly compares joint replacement (JR) and trapeziectomy techniques to provide an update as to which surgical intervention is superior for first carpometacarpal (CMC-1) joint osteoarthritis.

methodsIn August 2020, MEDLINE, Embase and Web of Science were searched for eligible studies that compared these two techniques for the treatment of CMC-1 joint osteoarthritis (PROSPERO registration ID: CRD42020189728). Primary outcomes included the Disabilities of the Arm, Shoulder and Hand (DASH), QuickDASH (QDASH) and pain visual analogue scale (VAS) scores. Secondary outcomes, such as total complication, dislocation and revision surgery rates, were also measured.

resultsFrom 1909 studies identified, 14 studies (1005 patients) were eligible. Our meta-analysis found that post-operative QDASH scores were lower for patients in the JR group (five studies, p = 0.0004). Similarly, significantly better postoperative key pinch strength in favour of JR was noted (three studies, p = 0.001). However, pain (VAS) scores were similar between the two groups (five studies, p = 0.21). Moreover, JR techniques had significantly greater odds of overall complications (12 studies; OR 2.12; 95% CI 1.13-3.96, p = 0.02) and significantly greater odds of revision surgery (9 studies; OR 5.14; 95% CI 2.06-12.81, p = 0.0004).

conclusionOverall, based on very low- to moderate-quality evidence, JR treatments may result in better function with less disability with comparable pain (VAS) scores; however, JR has greater odds of complications and greater odds of requiring revision surgery. More robust RCTs that compare JR and TRAP with standardised outcome measures and long-term follow-up would add to the overall quality of evidence.

Indexed as

Arthroplasty, ReplacementCarpometacarpal JointsOsteoarthritisTrapezium BoneHumansPainThumbFirst carpometacarpal (CMC 1)Joint replacementMeta-analysisOsteoarthritisSystematic reviewTrapeziectomy

Identifiers

PMID34244850
PMCPMC9279208
OpenAlexW3178264674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.