ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Getting a Grip on Secular Changes: Age-Period-Cohort Modeling of Grip Strength in the English Longitudinal Study of Ageing.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors associated with handgrip strength across the life course: A systematic review.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Trial
- A measurement comparability study to support instrument harmonization in the Canadian Longitudinal Study on Aging.American journal of epidemiology · 2026Article
- Grip strength indicators and successful aging among middle-aged and older adults: evidence from the CHARLS cohort.Scientific reports · 2026Article
- CD21Frontiers in aging · 2026Article
- Alcohol Consumption and Measures of Sarcopenic Muscle Risk: Cross-Sectional and Prospective Associations Within the UK Biobank Study.Calcified tissue international · 2023Article
- It Runs in the Family: Testing for Longitudinal Family Flynn Effects.Journal of Intelligence · 2023Article
- An integrative approach for the analysis of risk and health across the life course: challenges, innovations, and opportunities for life course research.Discover social science and health · 2023Review
- Inter-cohort shifts in chronic disease, dementia, and mortality.Biodemography and social biologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundGrip strength is a popular and valuable measure in studies of physical functional capabilities in old age. The influence of historical trends and differential period-specific exposures can complicate the interpretation of biomarkers of aging and health and requires careful analysis and interpretation of aging, birth cohort, and period effects. This study evaluates the effects of aging, period, and cohort on grip strength in a population of adults and older adults.
methodsWe use more than 27 000 observations for individuals at least 50 years of age, born in approximately 1910-1960, from the English Longitudinal Study of Ageing to examine a variety of multilevel and cross-classified modeling approaches to evaluate age, period, and cohort effects. Our results extended Hierarchical Age-Period-Cohort modeling and compared our results with a set of 9 submodels with explicit assumptions to determine the most reliable modeling approach.
resultsFindings suggest grip strength is primarily related to age, with minimal evidence of either period and/or cohort effects. Each year's increase in a person's age was associated with a 0.40-kg decrease in grip strength, though this decline differs by gender.
conclusionsWe conclude that as the population ages, grip strength declines at a systematic and predictable rate equal to -0.40 kg per year (approximately -0.50 kg for men and -0.30 kg for women) in residents of England aged 50 and older. Age effects were predominant and most consistent across methodologies. While there was some evidence for cohort effects, such effects were minimal and therefore indicative that grip strength is a consistent physiological biomarker of aging.
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