ArticleBone marrow transplantation2021
Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome.
Open access · hybridAbstract read
In one paragraph
Article in Bone marrow transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 40 citations in OpenAlex.
- Outcomes of germ line testing for children with hematologic malignancies undergoing hematopoietic cell transplantation.Blood advances · 2026Article
- Clinical characteristics and long-term treatment outcomes in childhood myelodysplastic neoplasm: a nationwide population-based study in Korea.BMC cancer · 2026Article
- Review
- GATA2 deficiency exacerbates chronic liver injuryWorld journal of stem cells · 2026Article
- Long-term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium.British journal of haematology · 2026Article
- Established and emerging non-cellular therapies in inherited bone marrow failure syndromes.Frontiers in immunology · 2026Review
- Pediatric Acute Megakaryoblastic Leukemia with a GATA2 Mutation and Monosomy 7: A Case Report and Clinical Management Challenges.Reports (MDPI) · 2025Article
- Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency.Head & neck · 2025Article
- Insights into PediatricBiomedicines · 2025Review
- Fatal thrombotic microangiopathy during induction for acute myeloid leukemia: A case report and review of vascular complications in germline GATA2 haploinsufficiency.British journal of haematology · 2025Article
- Insights into the Molecular Mechanisms of Genetic Predisposition to Hematopoietic Malignancies: The Importance of Gene-Environment Interactions.Cancer discovery · 2024Article
- The different faces of GATA2 deficiency: implications for therapy and surveillance.Frontiers in oncology · 2024Article
- Germline predisposition traits in allogeneic hematopoietic stem-cell transplantation for myelodysplastic syndromes: a survey-based study and position paper on behalf of the Chronic Malignancies Working Party of the EBMT.The Lancet. Haematology · 2023Review
- A Nationwide Study of GATA2 Deficiency in Italy Reveals Novel Symptoms and Genotype-phenotype Association.Journal of clinical immunology · 2023Article
- GATA2 Deficiency: Predisposition to Myeloid Malignancy and Hematopoietic Cell Transplantation.Current hematologic malignancy reports · 2023Review
- Of Mycelium and Men: Inherent Human Susceptibility to Fungal Diseases.Pathogens (Basel, Switzerland) · 2023Review
- Review
- αβT- and B-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation in children with myelodysplastic syndromes.Haematologica · 2022Article
- MonoMAC syndrome with GATA2 novel mutation: A case report.Leukemia research reports · 2022Article
- Case report: Successful allogeneic stem cell transplantation in a child with novel GATA2 defect associated B-cell acute lymphoblastic leukemia.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 19 institutions in 10 countries.
Rachel BortnickDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Marcin WlodarskiDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Valerie de HaasPrincess Maxima Center, Diagnostic Laboratory/DCOG Laboratory, Utrecht, The Netherlands.
Barbara De MoerlooseDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0002-2449-539X
Michael DworzakDepartment of Pediatrics, St. Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.
Henrik HasleDepartment of Pediatrics, Aarhus University Hospital Skejby, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-3976-9231
Riccardo MasettiDepartment of Pediatric Oncology and Hematology, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0002-1264-057X
Jan StarýDepartment of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.
Dominik TurkiewiczDepartment of Pediatric Oncology/Hematology, Skåne University Hospital, Lund, Sweden.
Marek UssowiczDepartment of Bone Marrow Transplantation, Oncology and Hematology, Wroclaw Medical University, Wroclaw, Poland.
Emilia KozyraDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-1107-8818
Michael AlbertDepartment of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU, Munich, Germany.ORCID http://orcid.org/0000-0001-9143-3263
Peter BaderDepartment for Children and Adolescents, Division for Stem Cell Transplantation and Immunology, University Hospital Frankfurt, Frankfurt am Main, Frankfurt, Germany.
Victoria BordonDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0001-8446-0220
Gunnar CarioDepartment of Pediatrics, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
Rita BeierDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Essen, Essen, Germany.
Johannes SchulteDepartment of Pediatric Oncology, Hematology and Stem Cell Transplantation, Charité University Medicine Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-0671-1201
Dorine BrestersPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Ingo MüllerDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-7477-6632
Herbert PichlerDepartment of Pediatrics, St. Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0001-5107-5123
Petr SedlacekDepartment of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.
Martin G SauerPediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.
Marco ZeccaPediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID http://orcid.org/0000-0002-8818-1744
Gudrun GöhringDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Ayami YoshimiDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Peter NoellkeDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0281-4732
Miriam ErlacherDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Franco LocatelliDepartment of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Sapienza, University of Rome, Rome, Italy.
Charlotte M NiemeyerDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-3856-7937
Brigitte StrahmDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. brigitte.strahm@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-6086-130X
for EWOG-MDS
University of Freiburg · DECharles University · CZGhent University Hospital · BEMedizinische Hochschule Hannover · DEPrincess Máxima Center · NLSt Anna Children's Hospital · ATAarhus University Hospital · DKBambino Gesù Children's Hospital · ITCharité - Universitätsmedizin Berlin · DEChristian-Albrechts-Universität zu Kiel · DEEssen University Hospital · DEGoethe University Frankfurt · DELudwig-Maximilians-Universität München · DEPoliclinico San Matteo Fondazione · ITSkåne University Hospital · SESt. Jude Children's Research Hospital · USUniversität Hamburg · DEUniversity of Bologna · ITWroclaw Medical University · PL
Funding
Wellcome Trust 109005
Abstract
GATA2 deficiency is a heterogeneous multi-system disorder characterized by a high risk of developing myelodysplastic syndrome (MDS) and myeloid leukemia. We analyzed the outcome of 65 patients reported to the registry of the European Working Group (EWOG) of MDS in childhood carrying a germline GATA2 mutation (GATA2
Indexed as
Graft vs Host DiseaseHematopoietic Stem Cell TransplantationMyelodysplastic SyndromesAdolescentChildChromosome DeletionGATA2 Transcription FactorGerm-Line MutationHumansGATA2 protein, humanGATA2 Transcription Factor
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.