Evidence map›Paper›PMID 34244568›Full record

ArticleScientific reports2021

Attenuated asthma phenotype in mice with a fetal-like antigen receptor repertoire.

Regine Stutz, Christopher Meyer, Elisabeth Kaiser, Sybelle Goedicke-Fritz, Harry W Schroeder, Robert Bals, Christoph Haertel, Tobias Rogosch, Sebastian Kerzel, Michael Zemlin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Regine StutzDepartment of General Pediatrics and Neonatology, Saarland University Medical School, Homburg, Germany.
Christopher MeyerDepartment of General Pediatrics and Neonatology, Saarland University Medical School, Homburg, Germany.
Elisabeth KaiserDepartment of General Pediatrics and Neonatology, Saarland University Medical School, Homburg, Germany.
Sybelle Goedicke-FritzDepartment of General Pediatrics and Neonatology, Saarland University Medical School, Homburg, Germany.
Harry W SchroederDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert BalsDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Saarland University Medical School, Homburg, Germany.
Christoph HaertelDepartment of Pediatrics, Würzburg University Medical Center, Würzburg, Germany.
Tobias RogoschDepartment of Pediatrics, Philipps-University Marburg, Marburg, Germany.
Sebastian KerzelDepartment of Pediatrics, Philipps-University Marburg, Marburg, Germany.
Michael ZemlinDepartment of General Pediatrics and Neonatology, Saarland University Medical School, Homburg, Germany. Michael.zemlin@uks.eu.
Saarland University · DEPhilipps University of Marburg · DEUniversity Hospital Regensburg · DEUniversity of Alabama at Birmingham · USUniversity of Würzburg · DE

Funding

Role of VpreB in immunoglobulin antigen binding site selectionR21AI134027 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SCHROEDER, HARRY WILLIAM · 2018 to 2019
$408k
NIAID NIH HHS R21 AI134027
6 · The paper itself

Abstract

We hypothesized that the scarcity of N-nucleotides might contribute to the inability of the neonate to mount a robust allergic immune response. To test this, we used terminal deoxyribunucleotidyl Transferase deficient (TdT

Indexed as

AnimalsAsthmaDisease Models, AnimalDNA NucleotidylexotransferaseGene DeletionImmunity, InnateInflammationMiceMice, Inbred BALB CDNA Nucleotidylexotransferase

Identifiers

PMID34244568
PMCPMC8270943
OpenAlexW3179254460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.