Evidence map›Paper›PMID 34244478›Full record

ReviewBlood cancer journal2021

Latest advances in the management of classical Hodgkin lymphoma: the era of novel therapies.

Razan Mohty, Rémy Dulery, Abdul Hamid Bazarbachi, Malvi Savani, Rama Al Hamed, Ali Bazarbachi, Mohamad Mohty

Abstract readReview
In one paragraph

Review in Blood cancer journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Predictive value of prognostic nutritional index as prognostic biomarkers in patients with lymphoma: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Razan Mohty *Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.ORCID 0000-0002-0189-8233
Rémy Dulery *Department of Hematology, Saint Antoine Hospital, AP-HP, Paris, France.
Abdul Hamid BazarbachiDepartment of Internal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, NY, USA.ORCID 0000-0003-0243-4040
Malvi SavaniDivision of Hematology and Oncology, Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
Rama Al HamedDepartment of Internal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Ali BazarbachiDivision of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Mohamad MohtyDepartment of Hematology, Saint Antoine Hospital, AP-HP, Paris, France. mohamad.mohty@inserm.fr.ORCID 0000-0002-7264-808X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hodgkin lymphoma is a highly curable disease. Although most patients achieve complete response following frontline therapy, key unmet clinical needs remain including relapsed/refractory disease, treatment-related morbidity, impaired quality of life and poor outcome in patients older than 60 years. The incorporation of novel therapies, including check point inhibitors and antibody-drug conjugates, into the frontline setting, sequential approaches, and further individualized treatment intensity may address these needs. We summarize the current treatment options for patients with classical Hodgkin lymphoma from frontline therapy to allogeneic hematopoietic stem cell transplantation and describe novel trials in the field.

Indexed as

Antineoplastic Agents, ImmunologicalDisease ManagementHematopoietic Stem Cell TransplantationHodgkin DiseaseHumansImmunoconjugatesQuality of LifeTransplantation, HomologousAntineoplastic Agents, ImmunologicalImmunoconjugates

Identifiers

PMID34244478
PMCPMC8270913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.