Evidence map›Paper›PMID 34244364›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Regional White Matter Scaling in the Human Brain.

Allysa Warling, Cassidy L McDermott, Siyuan Liu, Jakob Seidlitz, Amanda L Rodrigue, Ajay Nadig, Ruben C Gur, Raquel E Gur, David Roalf, Tyler M Moore and 4 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Allysa WarlingSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.ORCID https://orcid.org/0000-0001-9412-6357
Cassidy L McDermottSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
Siyuan LiuSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
Jakob SeidlitzSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
Amanda L RodrigueTommy Fuss Center for Neuropsychiatric Disease Research, Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Ajay NadigSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
Ruben C GurDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.
Raquel E GurDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.
David RoalfDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.
Tyler M MooreDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.ORCID https://orcid.org/0000-0002-1384-0151
David GlahnTommy Fuss Center for Neuropsychiatric Disease Research, Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Theodore D SatterthwaiteDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.
Edward T BullmoreDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom.ORCID https://orcid.org/0000-0002-8955-8283
Armin RaznahanSection on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892 raznahana@mail.nih.gov.
National Institute of Mental Health · USChildren's Hospital of Philadelphia · USBoston Children's Hospital · USUniversity of Pennsylvania · USUniversity of Cambridge · GBUniversity of the Arts · US

Funding

Section on Developmental NeurogenomicsZIAMH002949 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI RAZNAHAN, ARMIN · 2016 to 2025
$30.0M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Inter-modal Coupling Image AnalyticsR01MH112847 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Theodore Satterthwaite, Russell Takeshi Shinohara · 2017 to 2026
$5.9M
Evolution of Psychosis in Youth: Multimodal Risk and Resilience MarkersR01MH119219 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E, GUR, RUBEN C. · 2019 to 2023
$3.8M
Reproducible imaging-based brain growth charts for psychiatryR01MH120482 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI MILHAM, MICHAEL PETER, SATTERTHWAITE, THEODORE · 2019 to 2023
$3.5M
Intramural NIH HHS ZIA MH002949Medical Research Council MC_G0802534NICHD NIH HHS P50 HD105351NIMH NIH HHS R01 MH112847NIMH NIH HHS R01 MH119219NIMH NIH HHS R01 MH120482
6 · The paper itself

Abstract

Anatomical organization of the primate cortex varies as a function of total brain size, where possession of a larger brain is accompanied by disproportionate expansion of associative cortices alongside a relative contraction of sensorimotor systems. However, equivalent scaling maps are not yet available for regional white matter anatomy. Here, we use three large-scale neuroimaging datasets to examine how regional white matter volume (WMV) scales with interindividual variation in brain volume among typically developing humans (combined

Indexed as

AdolescentAdultAnisotropyBiological Variation, IndividualBrainChildCohort StudiesCorpus CallosumDiffusion Magnetic Resonance ImagingFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNonlinear Dynamicsneuroimagingscalingwhite matter

Identifiers

PMID34244364
PMCPMC8372020
OpenAlexW3179094782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.