Evidence map›Paper›PMID 34244355›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Sex Differences and Caffeine Impact in Adenosine-Induced Hyperemia.

Martin Lyngby Lassen, Christina Byrne, Majid Sheykhzade, Mads Wissenberg, Preetee Kapisha Hurry, Anne Vibeke Schmedes, Andreas Kjaer, Philip Hasbak

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  8. Positron Range Correction Helps Enhance the Image Quality of CardiacJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pulmonary blood volume assessment from a standard cardiac rubidium-82 imaging protocol: impact of adenosine-induced hyperemia.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  14. Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  15. Reply: Caffeine and fractional flow reserve overestimation: a word of caution.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
  16. Letter: Caffeine and fractional flow reserve overestimation: a word of caution.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Martin Lyngby LassenDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; martin.lyngby.lassen@regionh.dk.
Christina ByrneDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Majid SheykhzadeDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mads WissenbergDepartment of Cardiology, Copenhagen University Hospital, Gentofte, Denmark; and.
Preetee Kapisha HurryDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Anne Vibeke SchmedesDepartment of Biochemistry and Immunology, Lillebaelt Hospital, Vejle, Denmark.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Philip HasbakDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKCopenhagen University Hospital · DKGentofte Hospital · DKLillebaelt Hospital · DKRigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeine consumption before adenosine stress myocardial perfusion imaging (MPI) is known to affect the hemodynamic response and, thus, reduce the stress myocardial blood flow (MBF) and myocardial flow reserve (MFR) assessments. However, it is not clear if any sex-specific differences in the hemodynamic response after caffeine consumption exist. This study aimed to evaluate if such differences exist and, if so, their impact on MBF and MFR assessments.

Indexed as

Coronary Artery DiseaseHyperemiaMyocardial Perfusion ImagingAdenosineCaffeineCoronary CirculationFemaleHumansMalePositron-Emission TomographySex CharacteristicsTomography, X-Ray ComputedAdenosineCaffeineadenosinecaffeinemyocardial flow reservePETstress myocardial blood flow

Identifiers

PMID34244355
PMCPMC8978189
OpenAlexW3178500609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.