Evidence map›Paper›PMID 34244314›Full record

ArticleScience immunology2021

In vivo reprogramming of pathogenic lung TNFR2

Samira Mansouri, Himanshu Gogoi, Mauricio Pipkin, Tiago N Machuca, Amir M Emtiazjoo, Ashish K Sharma, Lei Jin

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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  5. Runx3 Regulates CD8International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Samira MansouriDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
Himanshu GogoiDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
Mauricio PipkinDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL 32610, USA.
Tiago N MachucaDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-0748-7590
Amir M EmtiazjooDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
Ashish K SharmaDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-1234-6039
Lei JinDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610, USA. lei.jin@medicine.ufl.edu.ORCID 0000-0001-6836-1142
University of Florida · US

Funding

Lung IDO-1+ TNFR2+ cDC2 subset in control of lung mucosal tolerance: Mechanism and ApplicationR01HL152163 · NHLBI · UNIVERSITY OF FLORIDA · PI JIN, LEI · 2021 to 2024
$1.8M
Mechanisms of STING-Mediated Mucosal Vaccine Adjuvant Activity of Cyclic di-GMPR01AI110606 · NIAID · UNIVERSITY OF FLORIDA · PI JIN, LEI · 2015 to 2019
$1.3M
Mechanisms of STING-dependent IFNgamma production during pulmonary pneumococcal infectionR21AI132865 · NIAID · UNIVERSITY OF FLORIDA · PI JIN, LEI · 2018 to 2019
$416k
Mechanisms of STING-Mediated Mucosal Vaccine Adjuvant Activity of Cyclic di-GMPR56AI110606 · NIAID · ALBANY MEDICAL COLLEGE · PI JIN, LEI · 2014 to 2014
$330k
NHLBI NIH HHS R01 HL152163NIAID NIH HHS R01 AI110606NIAID NIH HHS R21 AI132865NIAID NIH HHS R56 AI110606
6 · The paper itself

Abstract

Asthma is a common inflammatory lung disease with no known cure. Previously, we uncovered a lung TNFR2

Indexed as

Adoptive TransferAnimalsAsthmaCells, CulturedDendritic CellsDermatophagoides pteronyssinusDisease Models, AnimalFatty AcidsHumansImmune ToleranceImmunologic FactorsInterferon-alphaInterferon-betaLungMiceMice, Inbred C57BLFatty AcidsIfnar1 protein, mouseImmunologic FactorsInterferon-alphaInterferon-betaMapk1 protein, mouseMitogen-Activated Protein Kinase 1Receptor, Interferon alpha-betaReceptors, Tumor Necrosis Factor, Type IITnfrsf1b protein, mouse

Identifiers

PMID34244314
PMCPMC8323989
OpenAlexW3181355369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.