Evidence map›Paper›PMID 34244292›Full record

ArticleGenes & development2021

ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation.

Gustavo Antonio Urrutia, Haribaskar Ramachandran, Pierre Cauchy, Kyungjin Boo, Senthilkumar Ramamoorthy, Soeren Boller, Esen Dogan, Thomas Clapes, Eirini Trompouki, Maria-Elena Torres-Padilla and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Protein sumoylation in normal and cancer stem cells.Frontiers in molecular biosciences · 2022
    Review
  13. Sequences to Differences in Gene Expression: Analysis of RNA-Seq Data.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Gustavo Antonio Urrutia *Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Haribaskar Ramachandran *Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Pierre Cauchy *Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Kyungjin BooDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Senthilkumar RamamoorthyDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Soeren BollerDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Esen DoganDepartment of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Thomas ClapesDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Eirini TrompoukiDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.ORCID 0000-0002-7242-8810
Maria-Elena Torres-PadillaInstitute of Epigenetics and Stem Cells, Helmholtz Center Munich, 81377 Munich, Germany.
Jorma J PalvimoInstitute of Biomedicine, University of Eastern Finland, 70210 Kuopio, Finland.
Andrea PichlerDepartment of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
Rudolf GrosschedlDepartment of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.ORCID 0000-0002-0058-1250
Max Planck Institute of Immunobiology and Epigenetics · DEHelmholtz Zentrum München · DEUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The establishment of cell fates involves alterations of transcription factor repertoires and repurposing of transcription factors by post-translational modifications. In embryonic stem cells (ESCs), the chromatin organizers SATB2 and SATB1 balance pluripotency and differentiation by activating and repressing pluripotency genes, respectively. Here, we show that conditional

Indexed as

Embryonic Stem CellsSumoylationCell DifferentiationChromatinTranscription FactorsUbiquitin-Protein LigasesChromatinTranscription FactorsUbiquitin-Protein LigasesdifferentiationES cellLSD1pluripotencySATB1SATB2SUMO2ZFP451

Identifiers

PMID34244292
PMCPMC8336893
OpenAlexW3182762866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.