ArticleBMJ open2021
Implementation science protocol for a participatory, theory-informed implementation research programme in the context of health system strengthening in sub-Saharan Africa (ASSET-ImplementER).
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 17 citations in OpenAlex.
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- Epidemiology of acute myeloid leukemia in children and adolescents (1990-2021): a global burden of disease study.Die Naturwissenschaften · 2025Article
- A qualitative study of the palliative care needs of primary care patients with COPD: Experiences of COPD patients, their families and healthcare professionals.Palliative care and social practice · 2025Article
- The Lancet Psychiatry Commission: transforming mental health implementation research.The lancet. Psychiatry · 2024Review
- Sustaining the collaborative chronic care model in outpatient mental health: a matrixed multiple case study.Implementation science : IS · 2024Article
- Mobilising context as complex and dynamic in evaluations of complex health interventions.BMC health services research · 2023Article
- Health systems strengthening interventions for perinatal common mental disorders and experiences of domestic violence in Cape Town, South Africa: protocol for a pilot implementation study.Pilot and feasibility studies · 2022Article
- Challenges in Implementing the National Health Response to COVID-19 in Senegal.Global implementation research and applications · 2022Article
- A guide to systems-level, participatory, theory-informed implementation research in global health.BMJ global health · 2021Article
- Pills and prayers: a comparative qualitative study of community conceptualisations of pre-eclampsia and pluralistic care in Ethiopia, Haiti and Zimbabwe.BMC pregnancy and childbirth · 2021Article
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Authors and funding
15 authors at 4 institutions in 4 countries.
Funding
Abstract
objectivesASSET (Health System Strengthening in sub-Saharan Africa) is a health system strengthening (HSS) programme involving eight work-packages (ie, a research study that addresses a specific need for HSS) that aims to develop solutions that support high-quality care. Here we present the protocol for the implementation science (IS) theme within ASSET (ASSET-ImplmentER) that aims to understand what HSS interventions work, for whom and how, and how IS methodologies can be adapted to improve the HSS interventions within resource-poor contexts. SETTINGS: Publicly funded health facilities in rural and urban areas in in Ethiopia, South Africa, Sierra Leone, and Zimbabwe.
participantsResearch staff including principal investigators, coinvestigators, field staff, PhD students, and research assistants.
interventionsWork-packages use a mixed-methods effectiveness-effectiveness hybrid designs. At the end of the pre-implementation phase, a workshop is held whereby the IS theme, jointly with ASSET work-packages apply IS determinant frameworks to research findings to identify factors that influence the effectiveness of delivering evidence-informed care. Determinants are used to select a set of HSS interventions for further evaluation, where work-packages also theorise selective mechanisms.
conclusionsWe use a novel combination of IS methods at a programmatic level to facilitate comparisons of determinants and mechanisms that influence the effectiveness of HSS interventions in achieving implementation outcomes across different contexts. The study also contributes conceptual development and clarification at the underdeveloped interface of IS, HSS and global health.The ASSET-ImplementER theme is considered minimal risk as we only interview researchers involved in the different work-packages. To this effect we have received approval from King's College London Ethics Committee for research that is considered minimal risk (Reference number: MRA-20/21-21772).
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