Evidence map›Paper›PMID 34244252›Full record

ArticleBMJ open2021

The Danish HIV Birth Cohort (DHBC) - a nationwide, prospective cohort.

Nina Weis, Terese L Katzenstein, Mathilde Ørbæk, Merete Storgaard, Gitte Pedersen, Isik S Johansen, Ellen Moseholm

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark nina.weis@regionh.dk.ORCID 0000-0002-3133-2724
Terese L KatzensteinDepartment of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Mathilde ØrbækDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0003-0737-8076
Merete StorgaardDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Gitte PedersenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Isik S JohansenDepartment of Infectious Diseases, Odense Universitetshospital, Odense, Denmark.
Ellen MoseholmDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID 0000-0002-7195-8641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of the Danish HIV Birth Cohort (DHBC) is to investigate the significance of HIV-1 infection in pregnancy and after delivery in women living with HIV (WLWH) in Denmark and their children, in the era of antiretroviral therapy and other interventions for treatment and prophylaxis.

participantsAll WLWH giving birth to one or more children in Denmark after 31 December 1999 are included, with consecutive ongoing enrolment, if they are living with HIV and pregnant, or if they are diagnosed with HIV in relation to pregnancy, delivery or shortly after delivery. FINDINGS TO DATE: DHBC has been used to describe trends in the management of pregnancies in WLWH and their outcomes on a nationwide basis, mode of delivery and predictors of emergency caesarean section as well as risk factors during pregnancy in WLWH for birth-related complications compared with women from the general population (WGP). We have found that HIV-exposed, but uninfected (HEU) children born to WLWH had a lower median birth weight and gestational age and were at higher risk of intrauterine growth retardation than children born to WGP. We have investigated risk of in-hospital admission and use of antibiotics during the first 4 years of life among HEU children and showed that HEU children had an increased risk of overall hospital admission compared with a matched control group of unexposed children.Further, we compared anthropometric outcomes in children with a matched control group of children not exposed to HIV. FUTURE PLANS: To continuously investigate the significance of HIV infection and antiretroviral therapy in pregnancy and after delivery in WLWH in Denmark and their HEU children and compare these findings with children born to WGP.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousCesarean SectionChildDenmarkFemaleHumansPregnancyProspective StudiesepidemiologyHIV & AIDSreproductive medicine

Identifiers

PMID34244252
PMCPMC8268920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.