Evidence map›Paper›PMID 34244204›Full record

ArticleBMJ global health2021

Model for developing context-sensitive responses to vulnerability in research: managing ethical dilemmas faced by frontline research staff in Kenya.

Sassy Molyneux, Priya Sukhtankar, Johnstone Thitiri, Rita Njeru, Kui Muraya, Gladys Sanga, Judd L Walson, James Berkley, Maureen Kelley, Vicki Marsh

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Sassy MolyneuxKEMRI-Wellcome Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya smolyneux@kemri-wellcome.org.
Priya SukhtankarDepartment of Child Health, Gloucester Hospitals NHS Foundation Trust, Gloucester, UK.
Johnstone ThitiriKEMRI-Wellcome Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya.
Rita NjeruEthox Centre and Wellcome Centre for Ethics & Humanities, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Kui MurayaKemri-Wellcome Trust, Centre for Geographic Medicine Research Coast, Nairobi, Kenya.
Gladys SangaKEMRI-Wellcome Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya.
Judd L WalsonDepartment of Global Health, University of Washington, Seattle, Washington, USA.
James BerkleyKEMRI-Wellcome Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya.
Maureen KelleyEthox Centre and Wellcome Centre for Ethics & Humanities, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Vicki MarshKEMRI-Wellcome Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya.
University of Oxford · GBKenya Medical Research Institute · KEGloucestershire Hospitals NHS Foundation Trust · GBUniversity of Washington · USWellcome Centre for Ethics and Humanities · GB

Funding

EPA EP-C-15-003Medical Research Council MC_PC_16025Medical Research Council MR/M007367/1Wellcome TrustWellcome Trust 107769/Z/10/ZWellcome Trust 200344/Z/15/Z
6 · The paper itself

Abstract

Health research in low-resource settings often involves individuals and populations defined as 'vulnerable'. There is growing attention in the literature to the ethical dilemmas that frontline research staff face while conducting such research. However, there is little documented as to how research staff might support one another in identifying and handling these dilemmas in different contexts. Over the course of conducting empirical ethics research embedded in the Childhood Acute Illness & Nutrition Network, we developed an approach to examine and respond to the ethical issues and dilemmas faced by the study teams, particularly frontline staff. In this paper we describe the specific tools and approach we developed, which centred on regular cross-team ethics reflection sessions, and share lessons learnt. We suggest that all studies involving potentially vulnerable participants should incorporate activities and processes to support frontline staff in identifying, reflecting on and responding to ethical dilemmas, throughout studies. We outline the resources needed to do this and share piloted tools for further adaptation and evaluation. Such initiatives should complement and feed into-and certainly not in any way replace or substitute for-strong institutional ethics review, safeguarding and health and safety policies and processes, as well broader staff training and career support initiatives.

Indexed as

Biomedical ResearchVulnerable PopulationsAdultHumansKenyachild healthhospital-based studypaediatricspublic health

Identifiers

PMID34244204
PMCPMC8268889
OpenAlexW3180846682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.