Evidence map›Paper›PMID 34244106›Full record

ArticleRespiratory investigation2021

The effect of driving pressures in COVID-19 ARDS: Lower may still be better as in classic ARDS.

Süleyman Yildirim, Burcu Acar Cinleti, Saba Mukaddes Saygili, Emre Senel, Ozlem Ediboglu, Cenk Kirakli

Open access · greenAbstract read
In one paragraph

Article in Respiratory investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Süleyman YildirimUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey.
Burcu Acar CinletiUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey.
Saba Mukaddes SaygiliUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey.
Emre SenelUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey.
Ozlem EdibogluUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey.
Cenk KirakliUniversity of Health Sciences, Dr. Suat Seren Chest Disease and Chest Surgery Training and Research Hospital, Intensive Care Unit, İzmir, Turkey. Electronic address: ckirakli@hotmail.com.
Izmir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe respiratory dynamics of coronavirus disease 2019 (COVID-19) patients under invasive ventilation are still not well known. In this prospective cohort, we aimed to assess the characteristics of the respiratory system in COVID-19 patients under invasive mechanical ventilation and evaluate their relationship with mortality.

methodsFifty-eight COVID-19 patients who underwent invasive mechanical ventilation between March 11, 2020 and September 1, 2020 were enrolled for the present study. Demographics and laboratory values at baseline were recorded. Respiratory variables such as tidal volume, plateau pressure, positive end expiratory pressure, static compliance, and driving pressure were recorded daily under passive conditions. Further, the median values were analyzed.

resultsMedian age of the patients was 64 years (58-72). Mortality was 60% on day 28. Plateau pressure, driving pressure, and static compliance significantly differ between the survivors and non-survivors. When patients were categorized into two groups based on the median driving pressure (Pdrive) of ≤15 cmH

conclusionCOVID-19 related acute respiratory distress syndrome (ARDS) seemed to have similar characteristics as other forms of ARDS. Lung protective ventilation with low plateau and driving pressures might be related to lower mortality.

Indexed as

COVID-19Respiratory Distress SyndromeAgedHumansMiddle AgedProspective StudiesRespiration, ArtificialSARS-CoV-2Tidal VolumeAcute respiratory distress syndromeCOVID-19Driving pressurePlateau pressureStatic compliance

Identifiers

PMID34244106
PMCPMC8258546
OpenAlexW3178143893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.