Evidence map›Paper›PMID 34243904›Full record

ReviewSeminars in nuclear medicine2022

Clinical Management of COVID-19 Patients - An Update.

Martin Mølhave, Jane Agergaard, Christian Wejse

Abstract readReview
In one paragraph

Review in Seminars in nuclear medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Effect of Vitamin D in Long COVID Patients.International journal of environmental research and public health · 2023
    Article
  14. Secondary pulmonary infection byWorld journal of clinical cases · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. COVID-19-Associated Erythema Nodosum Detected on FDG PET/CT.Diagnostics (Basel, Switzerland) · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Martin MølhaveDept of Infectious Diseases, Institute for Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
Jane AgergaardDept of Infectious Diseases, Institute for Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
Christian WejseDept of Infectious Diseases, Institute for Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; GloHAU, Center for Global Health, Dept of Public Health, Aarhus University, Aarhus, Denmark. Electronic address: wejse@ph.au.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 virus may cause COVID-19 disease, which causes mild-to-moderate disease in 80% of laboratory-confirmed cases which may be community-managed. A considerable age-dependent mortality is seen among elderly and other at-risk populations but among young and healthy individuals it is < 0.5%. Long-term health issues have been reported following severe COVID-19 requiring hospitalization as well as after cases of mild COVID-19 without hospitalization. Upon receiving COVID-19 suspected patients at hospitals, patients should be isolated and PPE should be worn by all health staff when in contact with the patients. Additionally, patients are tested for the presence of SARS-CoV-2 RNA by PCR, and blood samples are drawn. Imaging is not pivotal for the diagnosis, but chest X-ray is a relevant examination for all and is used to determine severity and treatment need Abnormal findings on CT scans are found in most patients, most frequently peripheral ground-glass opacity and bilateral patchy shadowing are present. Patients are, according to their needs and risks, treated with oxygen therapy, anticoagulation therapy, steroids, antivirals, or immunosupressive drugs on special indications. Convalescent plasma therapy and monoclonal antibodies have a limited role in the treatment, mostly in severely immunocompromised patients. Patients with long-term sequelae should be evaluated in a post-COVID outpatient clinic. The most frequent reported symptoms include cognitive impairment, dyspnea, loss of smell and taste, and mental and physical fatigue although a wide spectrum of symptoms from other organ systems are also reported. The current treatment is based on symptom relief and rehabilitation as there is no documented specific medical treatment.

Indexed as

COVID-19AgedCOVID-19 SerotherapyHumansImmunization, PassiveRNA, ViralSARS-CoV-2RNA, Viral

Identifiers

PMID34243904
PMCPMC8206588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.