Evidence map›Paper›PMID 34243785›Full record

ArticleJournal of medical case reports2021

Superficial siderosis as a rare cause of visual and auditory pseudohallucinations: a case report.

Tobias Braun, Maxime Viard, Tobias Struffert, Omar AlhajOmar, Mesut Yeniguen, Martin Juenemann

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tobias BraunDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany. tobias.braun@neuro.med.uni-giessen.de.ORCID http://orcid.org/0000-0003-1738-2773
Maxime ViardDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Tobias StruffertDepartment of Neuroradiology, University Hospital Giessen and Marburg, Klinikstrasse 33, 35392, Giessen, Germany.
Omar AlhajOmarDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Mesut YeniguenDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Martin JuenemannDepartment of Neurology, University Hospital Giessen and Marburg, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Justus-Liebig-Universität Gießen · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuperficial siderosis is a rare disease involving hemosiderin deposits on the surface of brain or spinal cord that are thought to cause clinical symptoms, which usually consist of cranial nerve dysfunction, cerebellar ataxia, or myelopathy. Pseudohallucinations have been described as the patient being aware of the nonreality of hallucination-like phenomena. Data on pseudohallucinations of cerebral somatic origin are sparse. We present a case of auditory and visual pseudohallucinations due to superficial siderosis. Siderosis was diagnosed using cerebrospinal fluid analysis and magnetic resonance imaging as part of the clinical routine for newly emerged psychiatric symptoms. CASE PRESENTATION: An 84-year-old white/european female presented to our hospital with no prior history of psychiatric or neurological disease and no history of trauma. She reported seeing things and hearing voices singing to her for some days. She was aware these phenomena were not real (pseudohallucinations). On examination, no relevant abnormalities were detected. Cerebrospinal fluid analysis showed elevated ferritin. Magnetic resonance imaging with susceptibility-weighted sequences revealed diffuse superficial siderosis in several parts of the brain, among other occipital and temporal gyri. The pseudohallucinations resolved with a risperidone regime. The patient was treated with rivaroxaban because of atrial fibrillation. Potentially elevating the risk of further hemorrhage, this therapy was discontinued, and an atrial appendage occlusion device was implanted.

conclusionWe report the first case of pseudohallucinations in superficial siderosis. The risk of missing this diagnosis can be reduced by applying a standardized diagnostic pathway for patients presenting with the first episode of psychiatric symptoms. Somatic and potentially treatable causes should not be missed because they might lead to unnecessary treatments, stigmatization, and legal restrictions of self-determination, especially for elderly people.

Indexed as

SiderosisAgedAged, 80 and overBrainFemaleHallucinationsHemosiderinHumansMagnetic Resonance ImagingHemosiderinCase reportPseudohallucinationsSuperficial siderosis

Identifiers

PMID34243785
PMCPMC8272307
OpenAlexW3182646019

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.