Evidence map›Paper›PMID 34243744›Full record

Observational studyBMC pulmonary medicine2021

Classification of COPD patients and compliance to recommended treatment in Greece according to GOLD 2017 report: the RELICO study.

Nikolaos Tzanakis, Nikolaos Koulouris, Katerina Dimakou, Konstantinos Gourgoulianis, Epameinondas Kosmas, Georgia Chasapidou, Athanasios Konstantinidis, Christos Kyriakopoulos, Theodoros Kontakiotis, Aggeliki Rapti and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Real-Life Effectiveness of Aclidinium/Formoterol on COPD Control: The REDACT Observational Study.International journal of chronic obstructive pulmonary disease · 2026
    Observational
  2. Article
  3. Article
  4. Article
  5. Quality of Care and Outcomes of Inpatients with COPD: A Multi-Center Study in China.International journal of chronic obstructive pulmonary disease · 2025
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Are We Missing the Opportunity to Disseminate GOLD Recommendations Through AECOPD Discharge Letters?International journal of chronic obstructive pulmonary disease · 2023
    Article
  11. Article
  12. Observational
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Nikolaos TzanakisDepartment of Respiratory Medicine, University General Hospital of Heraklion, Heraklion, Greece.
Nikolaos Koulouris1st Department of Respiratory Medicine and Intensive Care Unit, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Katerina Dimakou5th Respiratory Medicine Department, General Hospital for Chest Diseases "SOTIRIA", Athens, Greece.
Konstantinos GourgoulianisDepartment of Respiratory Medicine, Faculty of Medicine, University of Thessaly, BIOPOLIS, 41500, Larissa, Greece.
Epameinondas KosmasDepartment of Pulmonary Medicine PNOH, Metropolitan Hospital, Neo Faliro, Greece.
Georgia ChasapidouDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Thessaloniki, Greece.
Athanasios KonstantinidisRespiratory Medicine Department, University Hospital of Ioannina, Ioannina, Greece.
Christos KyriakopoulosRespiratory Medicine Department, University Hospital of Ioannina, Ioannina, Greece.
Theodoros KontakiotisDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Thessaloniki, Greece.
Aggeliki Rapti2nd Respiratory Medicine Department, General Hospital for Chest Diseases "SOTIRIA", Athens, Greece.
Mina Gaga7th Respiratory Medicine Department, General Hospital for Chest Diseases "SOTIRIA", Athens, Greece.
Konstantinos KalafatakisDepartment of Informatics and Telecommunications, School of Informatics and Telecommunications, University of Ioannina, Arta, Greece.
Konstantinos KostikasRespiratory Medicine Department, University Hospital of Ioannina, Ioannina, Greece. ktkostikas@gmail.com.
Sotiria General Hospital · GRUniversity Hospital of Ioannina · GRG. Papanikolaou General Hospital · GRMetropolitan Hospital · GRNational and Kapodistrian University of Athens · GRUniversity Hospital of Heraklion · GRUniversity of Ioannina · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is a multifactorial clinical condition, characterized by chronic progressive (or worsening) respiratory symptoms, structural pulmonary abnormalities, and impaired lung function, and is often accompanied by multiple, clinically significant comorbid disorders. In 2017, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) issued a new report on COPD prevention, diagnosis and management, aiming at personalizing the maintenance therapeutic approach of the stable disease, based on the patients' symptoms and history of exacerbations (ABCD assessment approach). Our objective was to evaluate the implementation of GOLD suggestions in everyday clinical practice in Greece.

methodsThis was a cross-sectional observational study. Sixty-five different variables (demographics, vital sign measurements, COPD-related medical history parameters, comorbidities, vaccination data, COPD severity based on spirometry measurements, COPD stage based on the ABCD assessment approach, COPD treatments) were collected from 3615 nation-wide COPD patients (Greece).

resultsThe mean age at the time of initial COPD diagnosis was 63.8 (± 10.2). Almost 60% of the subjects were classified into group B, while the remaining patients were falling into groups A (18%) and D (21%), and only a small minority of patients belonged to Group C, according to the ABCD assessment approach. The compliance of respiratory physicians to the GOLD 2017 therapeutic suggestions is problematic, especially when it comes to COPD patients belonging to Group A.

conclusionOur data provide valuable information regarding the demographic and medical profile of COPD patients in Greece, the domains which the revised ABCD assessment approach may show some clinical significance on, and the necessity for medical practitioners dealing with COPD patients to adhere closer to international recommendations for the proper management of the disease.

Indexed as

Disease ProgressionPatient ComplianceAdultAgedAged, 80 and overCross-Sectional StudiesFemaleGreeceHumansMaleMiddle AgedPractice Guidelines as TopicPulmonary Disease, Chronic ObstructiveRisk FactorsSeverity of Illness IndexSpirometryABCD assessment toolChronic managementCOPDGOLD 2017 recommendations

Identifiers

PMID34243744
PMCPMC8268415
OpenAlexW3181257203

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.