Evidence map›Paper›PMID 34242924›Full record

ArticleSleep medicine2021

Validity and reliability of the suggested immobilization test for measurement of restless legs syndrome severity in adults with multiple sclerosis.

Katie L J Cederberg, Arthur S Walters, Amy W Amara, Tiffany J Braley, Morgan L Schuetz, Brianna G Mathison, Robert W Motl

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Discrepancies between self-reported and device-measured sleep parameters in adults with multiple sclerosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Katie L J CederbergDepartment of Psychiatry and Behavioral Sleep Medicine, Stanford University, Stanford, CA, USA. Electronic address: kcederb@uab.edu.
Arthur S WaltersDepartment of Neurology, Vanderbilt University, Nashville, TN, USA.
Amy W AmaraDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Tiffany J BraleyDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Morgan L SchuetzDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Brianna G MathisonDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert W MotlDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USStanford University · USUniversity of Michigan–Ann Arbor · USVanderbilt University · US

Funding

Restless legs syndrome and physical activity in adults with multiple sclerosisF31HD097903 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CEDERBERG, KATIE L.J. · 2019 to 2020
$60k
NICHD NIH HHS F31 HD097903
6 · The paper itself

Abstract

OBJECTIVE/

backgroundAdults with multiple sclerosis (MS) often present with conditions that mimic restless legs syndrome (RLS), thereby adding complexity into the assessment of RLS severity. The current gold-standard measures of RLS severity rely on a fixed seven-day time frame, which limits the ability of these measures for studying acute changes in RLS severity. The present study examined if subjective and objective scores from the suggested immobilization test (SIT) provide a valid and reliable acute measure of RLS severity in persons with MS. PATIENTS/

methodsParticipants with MS and RLS (n = 20) and MS without RLS (n = 20) were matched by age, gender, and disability. All participants completed validated questionnaires for RLS severity followed by the SIT, conducted at 18:00 (±15 min) on the same day of the week for two consecutive weeks. Participants wore accelerometer devices for seven nights to capture periodic limb movements (PLMs) during the night.

resultsSelf-reported RLS severity during the SIT had excellent construct validity and convergent validity, but moderate test-retest reliability. Device-measured PLMs, while not themselves a direct measure of RLS severity, were significantly associated with PLMs during the night and had excellent test-retest reliability during the SIT in adults with MS.

conclusionsOur results suggest that the SIT represents a valid acute measure for capturing self-reported sensory aspects of RLS severity and should be considered in future research and clinical practice as a standardized acute measure of subjective RLS severity in adults with MS who present with RLS.

Indexed as

Multiple SclerosisRestless Legs SyndromeAdultHumansMovementReproducibility of ResultsSurveys and QuestionnairesMultiple sclerosisPeriodic limb movementsReliabilityRestless legs syndromeSeverityValidity

Identifiers

PMID34242924
PMCPMC8355084
OpenAlexW3167498052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.