Evidence map›Paper›PMID 34242438›Full record

ReviewExperimental physiology2022

Therapeutic benefits of proning to improve pulmonary gas exchange in severe respiratory failure: focus on fundamentals of physiology.

Ronan M G Berg, Jacob Peter Hartmann, Ulrik Winning Iepsen, Regitse Højgaard Christensen, Andreas Ronit, Anne Sofie Andreasen, Damian M Bailey, Jann Mortensen, Pope L Moseley, Ronni R Plovsing

Open access · hybridAbstract readReview
In one paragraph

Review in Experimental physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Observational
  9. Observational
  10. Understanding Acute Respiratory Distress Syndrome in High-Altitude Environments: A Comprehensive Review of Diagnosis and Treatment.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Review
  11. Awake prone positioning in acute hypoxaemic respiratory failure.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  12. Article
  13. Covid-19 special issue editorial.Experimental physiology · 2022
    Article
  14. Review
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ronan M G BergDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5757-9506
Jacob Peter HartmannDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ulrik Winning IepsenCentre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-8140-2583
Regitse Højgaard ChristensenCentre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Andreas RonitDepartment of Infectious Diseases, Copenhagen University Hospital - Hvidovre Hospital, Hvidovre, Denmark.
Anne Sofie AndreasenDepartment of Anaesthesia and Intensive Care, Copenhagen University Hospital - Herlev Hospital, Herlev, Denmark.
Damian M BaileyNeurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.ORCID 0000-0003-0498-7095
Jann MortensenDepartment of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Pope L MoseleyNovo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ronni R PlovsingDepartment of Anaesthesia and Intensive Care, Copenhagen University Hospital - Hvidovre Hospital, Hvidovre, Denmark.
University of Copenhagen · DKHvidovre Hospital · DKCopenhagen University Hospital · DKUniversity of South Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NEW

findingsWhat is the topic of this review? The use of proning for improving pulmonary gas exchange in critically ill patients. What advances does it highlight? Proning places the lung in its 'natural' posture, and thus optimises the ventilation-perfusion distribution, which enables lung protective ventilation and the alleviation of potentially life-threatening hypoxaemia in COVID-19 and other types of critical illness with respiratory failure. ABSTRACT: The survival benefit of proning patients with acute respiratory distress syndrome (ARDS) is well established and has recently been found to improve pulmonary gas exchange in patients with COVID-19-associated ARDS (CARDS). This review outlines the physiological implications of transitioning from supine to prone on alveolar ventilation-perfusion (

Indexed as

COVID-19Respiratory Distress SyndromeRespiratory InsufficiencyHumansHypoxiaProne PositionPulmonary Gas ExchangeRespiration, Artificialacute respiratory distress syndromeCOVID-19gas exchangegravityrespiratory failureSARS-CoV-2

Identifiers

PMID34242438
PMCPMC9290689
OpenAlexW3179654280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.