Evidence map›Paper›PMID 34241978›Full record

ReviewHarvard review of psychiatry

Leveraging Systems Science to Promote the Implementation and Sustainability of Mental Health and Psychosocial Interventions in Low- and Middle-Income Countries.

M Claire Greene, Terry T K Huang, Ali Giusto, Kathryn L Lovero, Melissa A Stockton, Rachel C Shelton, Palmira Dos Santos, Francisco Saúte, Milton L Wainberg

Abstract readReview
In one paragraph

Review in Harvard review of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Applying systems theory to global mental health.Global mental health (Cambridge, England) · 2025
    Article
  7. Article
  8. Article
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  10. Review
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  14. Article
  15. Article
  16. Leveraging Neuroscience to Fight Stigma Around Mental Health.Frontiers in behavioral neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M Claire GreeneFrom the Program on Forced Migration and Health, Heilbrunn Department of Population and Family Health (Dr. Greene) and Department of Sociomedical Science (Dr. Shelton), Columbia University Mailman School of Public Health; Center for Systems and Community Design and Department of Health Policy and Management, City University of New York Graduate School of Public Health and Health Policy (Dr. Huang); Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons & New York State Psychiatric Institute (Drs. Giusto, Lovero, Stockton, and Wainberg); Mental Health Department, Center for Applied Psychology and Psychometric Tests, Mozambique Ministry of Health (Dr. dos Santos); Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique (Dr. Saúte).
Terry T K Huang
Ali Giusto
Kathryn L Lovero
Melissa A Stockton
Rachel C Shelton
Palmira Dos Santos
Francisco Saúte
Milton L Wainberg

Funding

NYU-CUNY Prevention Research CenterU48DP006396 · DP · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUANG, TERRY T-K, THORPE, LORNA · 2018 to 2023
$9.1M
Global Mental Health Research Fellowship: Interventions That Make a DifferenceT32MH096724 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2012 to 2026
$4.4M
PALOP MENTAL HEALTH IMPLEMENTATION RESEARCH TRAININGD43TW009675 · FIC · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Lidia Gouveia, Maria A Oquendo · 2014 to 2026
$3.2M
ACL HHS U48DP006396FIC NIH HHS D43 TW009675NCCDPHP CDC HHS U48 DP006396NIMH NIH HHS T32 MH096724
6 · The paper itself

Abstract

abstractAdvancements in global mental health implementation research have revealed promising strategies for improving access to evidence-based mental health care. These advancements have not translated, however, into a reduced prevalence of mental disorders. In this review we examine the relationships between determinants (i.e., barriers and facilitators) and outcomes of mental health services in low- and middle-income countries to identify opportunities for improving the population-level impact and sustainability of innovations in global mental health. We identified three key implementation and services outcomes that influenced the prevalence of mental disorders in the 56 included review articles: supply (access, implementation), demand (help seeking, utilization), and quality (effectiveness, quality of care) of mental health services. Determinants of these outcomes revealed seven themes: community stakeholder engagement; cultural relevance; stigma; human resource capacity; organization of services; governance, policy, and financing; and sociopolitical and community context. We developed a causal loop diagram to illustrate the relationships among these determinants and outcomes. The causal loop diagram revealed the central role of community stakeholder engagement in bridging implementation and patient outcomes, the importance of addressing stigma and social determinants of mental health, and the need to complement supply-side implementation strategies with approaches to equilibrate demand and improve the quality of services. Applying systems science methodologies to global mental health research presents an opportunity to examine the complex relationships among community and health system factors that influence implementation of evidence-based interventions in order to identify sustainable approaches to improve the population-level impact of mental health services in low- and middle-income countries.

Indexed as

Mental DisordersMental Health ServicesDeveloping CountriesHumansMental HealthPsychosocial Intervention

Identifiers

PMID34241978
PMCPMC9162158

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.