Evidence map›Paper›PMID 34241964›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Antibodies, boosters, and optimizing SARS-CoV-2 vaccines for transplantation: A call for more research.

Michael G Ison, Emily Blumberg, Natasha Halasa, Dan Kaul, Nicole M Theodoropoulos, Cameron R Wolfe

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Protecting kidney transplant recipients against SARS-CoV-2 infection: A third dose of vaccine is necessary now.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  4. Review
  5. Boosters and optimizing SARS-CoV-2 vaccine for transplantation: No time to wait.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Michael G IsonDivisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3347-9671
Emily BlumbergDivision of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-5193-6170
Natasha HalasaDivision of Pediatric Infectious Diseases, Vanderbilt University, Nashville, Tennessee, USA.
Dan KaulDivision of Infectious Diseases, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-0990-4148
Nicole M TheodoropoulosDivision of Infectious Diseases, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0003-3009-8232
Cameron R WolfeDivision of Infectious Diseases, Duke University, Durham, North Carolina, USA.
Duke University · USNorthwestern University · USUniversity of Massachusetts Chan Medical School · USUniversity of Michigan · USUniversity of Pennsylvania · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite emerging data suggesting reduced antibody responses among solid organ transplant recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.

Indexed as

COVID-19COVID-19 VaccinesAntibodies, ViralHumansProspective StudiesSARS-CoV-2Antibodies, ViralCOVID-19 Vaccines

Identifiers

PMID34241964
PMCPMC8441892
OpenAlexW3178254674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.