ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2022
Post-COVID-19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound.
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Liver injury in post-acute COVID-19 syndrome: A systematic review and meta-analysis of early observational studies.Canadian liver journal · 2024Pooled it
- Multiparametric Ultrasound Assessment of Long-Term Liver Damage in COVID-19: Results of a Three-Year Follow-Up Study.Medicina (Kaunas, Lithuania) · 2026Article
- Liver-Related COVID-19 Consequences: Dynamics of Liver Health in 2.5 Years.Journal of clinical medicine · 2025Article
- Long-Term Manifestations of COVID-19: A Review.Cureus · 2025Review
- Alterations of hepatic lipid content following COVID-19 in persons with type 2 diabetes.BMJ open diabetes research & care · 2025Observational
- New Onset of Acute and Chronic Hepatic Diseases Post-COVID-19 Infection: A Systematic Review.Biomedicines · 2024Review
- Assessment of the liver with two-dimensional shear wave elastography following COVID-19 infection: A pilot study.Australasian journal of ultrasound in medicine · 2024Article
- Effect of SARS-CoV-2 infection on the liver.World journal of virology · 2023Review
- Liver involvement in patients with COVID-19 infection: A comprehensive overview of diagnostic imaging features.World journal of gastroenterology · 2023Review
- Acute-on-chronic liver failure in patients with severe acute respiratory syndrome coronavirus 2 infection.World journal of hepatology · 2023Review
- COVID-19: Has the Liver Been Spared?International journal of molecular sciences · 2023Review
- Association of human leukocyte antigen class II alleles with epithelial cell apoptosis and extracellular matrix production in acute COVID-19.Central-European journal of immunology · 2023Article
- Article
- Abdominal Imaging Findings in Patients with COVID-19 Part 2: Solid Organs.Middle East journal of digestive diseases · 2022Review
- Multisystemic Inflammatory Syndrome in Children, A Disease with Too Many Faces: A Single-Center Experience.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesThis study aimed to define patterns of liver injury after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using multiparametric ultrasound (mpUS) in a variable patient population with differing severities of COVID-19.
methodsNinety patients were enrolled into the study: 56 had SARS-CoV-2 3-9 months prior to enrolment; 34 served as a clinically healthy control group. All patients underwent an mpUS evaluation of the liver (elastography, dispersion and attenuation imaging). Seventy-six patients had abdominal magnetic resonance (MR) and noncontrast enhanced thoracic computed tomography (CT) scans performed at the same day. All patients were screened for biochemical markers of liver injury.
resultsLiver elasticity, viscosity, and steatosis values were significantly altered in patients after COVID-19, with particularly higher fibrosis scores compared to the control group (P < .001). Increased biochemical markers of liver injury correlated with changes in mpUS (P < .05), but not with findings on CT or MR findings. Seventeen of 34 hospitalized patients had a moderate or severe course of the disease course with more pronounced changes in mpUS. Increased body mass index was found to influence liver injury and correlated with more severe forms of COVID-19 (P < .001).
conclusionsCOVID-19 can cause liver injury observable using mpUS. More severe forms of COVID-19 and patient obesity are related to increased values of liver damage observed. In comparison to MRI and CT, mpUS appears to be more sensitive to involvement of liver parenchyma. Further research is warranted to establish this promising method for evaluating post-COVID-19 liver involvement in the aftermath of the pandemic.
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