ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2021
Severe outbreak of bovine neonatal diarrhea in a dairy calf rearing unit with multifactorial etiology.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of Probiotic Compounds as Feed Additives on Performance, Rumen Fermentation and Metabolic Blood Indices During the Preweaning Period of Holstein Dairy Calves.Animals : an open access journal from MDPI · 2026Article
- Screening and dynamic change study of microbial and metabolite markers for calf diarrhea based on multi-omics and machine learning.mSystems · 2026Article
- A DPO-Enhanced Gold Nanoparticle-Assisted PCR Assay for Simultaneous Detection of Bovine Viral Diarrhea Virus, Astrovirus, and Rotavirus.Animals : an open access journal from MDPI · 2026Article
- Identification of Cryptosporidium and Eimeria associated with diarrhea in calves in Japan (2020-2022).Parasitology research · 2026Article
- Outbreak of BVDV-1b associated with persistent infection, reproductive losses, and congenital malformations in beef cattle in Southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Longitudinal study of frequency of diarrhea and rotavirus species A in suckling calves from a small-scale family dairy farm in Brazil.Veterinary research communications · 2025Article
- Metagenomic Investigation of Pathogenic RNA Viruses Causing Diarrhea in Sika Deer Fawns.Viruses · 2025Article
- Review
- Age-stratified gut microbial changes in diarrheal calves: insights from 16S rRNA sequencing across early development.Frontiers in microbiology · 2025Article
- RAA-CRISPR/Cas12a-based visual field detection system for rapid and sensitive diagnosis of major viral pathogens in calf diarrhea.Frontiers in cellular and infection microbiology · 2025Article
- Identification of Recombinant Aichivirus D in Cattle, Italy.Animals : an open access journal from MDPI · 2024Article
- Development of the Intestinal Microbiota of Dairy Calves and Changes Associated withMicroorganisms · 2024Article
- Serological Profile for Major Respiratory Viruses in Unvaccinated Cows from High-Yielding Dairy Herds.Animals : an open access journal from MDPI · 2024Article
- Detection of drug resistance inFrontiers in veterinary science · 2024Article
- Immunohistochemical identification of a malignant catarrhal fever virus in cattle with renal diseases from Paraná state, Southern Brazil: a retrospective epidemiological study.Tropical animal health and production · 2023Article
- Association of ovine gammaherpesvirus 2 with an outbreak of acute respiratory disease in dairy cattle.Scientific reports · 2023Article
- Detection of the dominant pathogens in diarrheal calves of Ningxia, China in 2021-2022.Frontiers in veterinary science · 2023Article
- Molecular Detection and Genetic Characterization of Bovine Kobuvirus (BKV) in Diarrhoeic Calves in a Central Italy Herd.Transboundary and emerging diseases · 2023Article
- Modulating gastrointestinal microbiota to alleviate diarrhea in calves.Frontiers in microbiology · 2023Review
- Occurrence ofPathogens (Basel, Switzerland) · 2022Article
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Authors and funding
11 authors at 1 institution in 1 country.
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Abstract
This study describes the etiological diversity observed in a severe neonatal diarrhea outbreak with morbidity and mortality rates of 80 and 20%, respectively, with detection of mixed infections with viral, bacterial, and protozoan disease agents in a dairy calf rearing unit. Diarrheic fecal samples were collected from eight 5 to 18 days of age calves and were submitted to the investigation of the presence of rotavirus A (RVA), bovine coronavirus (BCoV), bovine kobuvirus (BKV), bovine viral diarrhea virus 1 and 2 (BVDV-1 and BVDV-2), enteropathogenic Escherichia coli (ETEC), Salmonella sp., and Cryptosporidium spp. Fragments of the small intestine of one calf with diarrhea that spontaneously died were submitted for histopathological analyses. The most frequent infectious agent detected in diarrheic fecal samples was BKV (8/8-100%), followed by RVA (5/8-62.5%), BVDV (5/8-62.5%), Cryptosporidium parvum (5/8-62.5%), ETEC (4/8-50%), and Cryptosporidium ryanae (1/8-12.5%). These etiological agents were found in mixed infections with two or more pathogens per diarrheic fecal sample. The association of viral and protozoan pathogens was the most frequently identified (37.5%) in these samples, followed by viral and bacterial (25%); viral, bacterial, and protozoan (25%); and only viral agents (12.5%). BCoV and Salmonella sp. were not identified in the diarrheic fecal samples analyzed. Additionally, histopathology of the small intestine diagnosed chronic lymphocytic enteritis. In conclusion, in calf rearing units, the adoption and strict monitoring of health management practices are critical to the success of this calf creation system.
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