ReviewInternational journal of clinical oncology2021
The role of lymph nodes in cervical cancer: incidence and identification of lymph node metastases-a literature review.
Review in International journal of clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- The false-negative rate of sentinel lymph node biopsy and its related factors in early-stage cervical cancer: a systematic review and meta-analysis.Acta oncologica (Stockholm, Sweden) · 2026Pooled it
- Noninvasive prediction of lymph-vascular space invasion in cervical cancer based on ultrasomics nomogram.BMC cancer · 2026Article
- A Novel, Promising Technique for Metastatic Lymph Node Detection in Uterine Cervical Cancer.Radiology. Imaging cancer · 2026Article
- GSDMD Promotes Epithelial-Mesenchymal Transition and Lymph Node Metastasis in Cervical Cancer in vitro and in vivo.Journal of inflammation research · 2026Article
- Gene Mutations and Related Molecular Events in Distant Metastasis of Cervical Cancer: A Review.International journal of medical sciences · 2026Review
- Integrating neutrophil-to-lymphocyte ratio into cervical cancer management: implications for prognostic assessment and therapeutic strategies - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- The Demographics and Outcomes of Women With Stage II Endometrial Cancer Diagnosed in Australia 2005-2007.The Australian & New Zealand journal of obstetrics & gynaecology · 2025Article
- Comparative study of five-year cervical cancer cause-specific survival prediction models based on SEER data.Scientific reports · 2025Article
- A Multicenter Study on the Relationship of Tumor Lesion Location with Bilateral Parametrial Involvement and Pelvic Lymph Node Metastasis in Cervical Squamous Cell Carcinoma.Annals of surgical oncology · 2025Article
- Radical hysterectomy or chemoradiotherapy for clinically early-stage cervical cancer with suspicious lymph nodes on imaging: a retrospective cohort study.Journal of gynecologic oncology · 2025Article
- Sentinel Lymph Node Detection in Cervical Cancer: Challenges in Resource-Limited Settings with High Prevalence of Large Tumours.Journal of clinical medicine · 2025Article
- Semantic-Attention Enhanced DSC-Transformer for Lymph Node Ultrasound Classification and Remote Diagnostics.Bioengineering (Basel, Switzerland) · 2025Article
- Expression Profile of Thymidine Kinase Genes in Cervical Squamous Cell Carcinoma Confirmed by Various Detection Methods.World journal of oncology · 2025Article
- Risk factors for pelvic lymph node metastasis in cervical cancer: a retrospective analysis of 186 patients.Frontiers in oncology · 2025Article
- Should all cervical cancer patients with positive lymph node receive definitive radiotherapy: a population-based comparative study.Archives of gynecology and obstetrics · 2025Article
- Article
- Risk Factor Analysis and Prediction of Para-Aortic Lymph Node Metastases in Locally Advanced Cervical Cancer.Cancer medicine · 2024Article
- Article
- The value of multiparameter MRI of early cervical cancer combined with SCC-Ag in predicting its pelvic lymph node metastasis.Frontiers in oncology · 2024Article
- Lymph node assessment in cervical cancer: current approaches.Frontiers in oncology · 2024Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Correct identification of patients with lymph node metastasis from cervical cancer prior to treatment is of great importance, because it allows more tailored therapy. Patients may be spared unnecessary surgery or extended field radiotherapy if the nodal status can be predicted correctly. This review captures the existing knowledge on the identification of lymph node metastases in cervical cancer. The risk of nodal metastases increases per 2009 FIGO stage, with incidences in the pelvic region ranging from 2% (stage IA2) to 14-36% (IB), 38-51% (IIA) and 47% (IIB); and in the para-aortic region ranging from 2 to 5% (stage IB), 10-20% (IIA), 9% (IIB), 13-30% (III) and 50% (IV). In addition, age, tumor size, lymph vascular space invasion, parametrial invasion, depth of stromal invasion, histological type, and histological grade are reported to be independent prognostic factors for the risk of nodal metastases. Furthermore, biomarkers can contribute to predict a patient's nodal status, of which the squamous cell carcinoma antigen (SCC-Ag) is currently the most widely used in squamous cell cervical cancer. Still, pre-treatment lymph node assessment is primarily performed by imaging, of which diffusion-weighted magnetic resonance imaging has the highest sensitivity and 2-deoxy-2-[
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.