Evidence map›Paper›PMID 34241695›Full record

ArticleAmino acids2021

Dietary L-arginine supplementation during days 14-25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts.

Cui Zhu, Xilong Li, Fuller W Bazer, Gregory A Johnson, Robert C Burghardt, Zongyong Jiang, Guoyao Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The "ideal protein" concept is not ideal in animal nutrition.Experimental biology and medicine (Maywood, N.J.) · 2022
    Article
  6. Article
  7. Article
  8. Nutritional and Physiological Regulation of Water Transport in the Conceptus.Advances in experimental medicine and biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Cui Zhu *Department of Animal Science, Texas A&M University, College Station, TX, 77843, USA.
Xilong Li *Department of Animal Science, Texas A&M University, College Station, TX, 77843, USA.
Fuller W BazerDepartment of Animal Science, Texas A&M University, College Station, TX, 77843, USA.
Gregory A JohnsonDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, 77843, USA.
Robert C BurghardtDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, 77843, USA.
Zongyong JiangInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, Guangdong, China.
Guoyao WuDepartment of Animal Science, Texas A&M University, College Station, TX, 77843, USA. g-wu@tamu.edu.ORCID http://orcid.org/0000-0001-8058-6969
Texas A&M University · USGuangdong Academy of Agricultural Sciences · CN

Funding

Texas A&M AgriLife Research H8200U.S. Department of Agriculture #2015-67015-23276
6 · The paper itself

Abstract

This study tested the hypothesis that dietary L-arginine (Arg) supplementation to pregnant gilts enhanced the expression of water channel proteins [aquaporins (AQPs)] in their placentae and endometria. Gilts were fed twice daily 1 kg of a corn and soybean meal-based diet supplemented with 0.0%, 0.4%, or 0.8% Arg between Days 14 and 25 of gestation. On Days 25 and 60 of gestation, gilts were hysterectomized to obtain placentae and endometria. On Day 25 of gestation, supplementation with 0.4% Arg increased (P < 0.05) the abundance of placental AQP9 protein, whereas supplementation with 0.8% Arg increased (P < 0.05) placental AQP1 and AQP9 proteins, compared with controls. On Day 60 of gestation, supplementation with 0.4% Arg increased (P < 0.05) endometrial AQP1 protein, whereas supplementation with 0.8% Arg increased (P < 0.05) endometrial AQP5 and AQP9 proteins. Supplementation with 0.8% Arg increased the endometrial expression of AQP1, AQP5, and AQP9 proteins located in the luminal epithelium and glandular epithelium of endometria, and placental transport of

Indexed as

Dietary SupplementsAnimalsAquaporinsArginineEndometriumFemalePlacentaPregnancySwineAquaporinsArginineAquaporinArginineGiltsPlacentaWater transport

Identifiers

PMID34241695
OpenAlexW3179563507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.