Evidence map›Paper›PMID 34241577›Full record

ArticleRNA biology2021

Structural and functional insights into human tRNA guanine transgylcosylase.

Katharina Sievers, Luisa Welp, Henning Urlaub, Ralf Ficner

Abstract read
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Cryo-EM reveals thatProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Queuosine tRNA Modification: Connecting the Microbiome to the Translatome.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharina SieversDepartment of Molecular Structural Biology, University of Göttingen, Göttingen, Germany.
Luisa WelpBioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Henning UrlaubBioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Ralf FicnerDepartment of Molecular Structural Biology, University of Göttingen, Göttingen, Germany.ORCID 0000-0002-1739-6086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eukaryotic tRNA guanine transglycosylase (TGT) is an RNA modifying enzyme incorporating queuine, a hypermodified guanine derivative, into the tRNAs

Indexed as

Crystallography, X-RayGuanineHumansModels, MolecularMutagenesis, Site-DirectedMutationPentosyltransferasesProtein ConformationRNA, TransferGuaninePentosyltransferasesqueuine tRNA-ribosyltransferaseRNA, TransfereukaryoticheterodimerQueuineRNA-binding proteinstructural biologytransglycosylasetRNA modificationX-ray crystallography

Identifiers

PMID34241577
PMCPMC8677009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.