Evidence map›Paper›PMID 34241550›Full record

Trial reportRadiology. Imaging cancer2021

Radiomic Features at CT Can Distinguish Pancreatic Cancer from Noncancerous Pancreas.

Po-Ting Chen, Dawei Chang, Huihsuan Yen, Kao-Lang Liu, Su-Yun Huang, Holger Roth, Ming-Shiang Wu, Wei-Chih Liao, Weichung Wang

Erratum issuedOpen access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Radiology. Imaging cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Review
  7. Catching pancreatic cancer early: Are we there yet?Journal of the National Cancer Center · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Radiomics in differential diagnosis of pancreatic tumors.European journal of radiology open · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Po-Ting ChenFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).ORCID 0000-0002-8675-5863
Dawei ChangFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
Huihsuan YenFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).ORCID 0000-0002-8687-5128
Kao-Lang LiuFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
Su-Yun HuangFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
Holger RothFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
Ming-Shiang WuFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
Wei-Chih LiaoFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).ORCID 0000-0001-5362-6953
Weichung WangFrom the Department of Medical Imaging (P.T.C., K.L.L.) and Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.S.W., W.C.L.), National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan; Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan (D.C., W.W.); Graduate Program of Data Science, National Taiwan University and Academia Sinica, Taipei, Taiwan (H.Y.); Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (S.Y.H.); NVIDIA, Bethesda, Md (H.R.); and Department of Medical Imaging, National Taiwan University Cancer Center, Taipei, Taiwan (K.L.L.).
National Taiwan University · TWNvidia (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To identify distinguishing CT radiomic features of pancreatic ductal adenocarcinoma (PDAC) and to investigate whether radiomic analysis with machine learning can distinguish between patients who have PDAC and those who do not. Materials and Methods This retrospective study included contrast material-enhanced CT images in 436 patients with PDAC and 479 healthy controls from 2012 to 2018 from Taiwan that were randomly divided for training and testing. Another 100 patients with PDAC (enriched for small PDACs) and 100 controls from Taiwan were identified for testing (from 2004 to 2011). An additional 182 patients with PDAC and 82 healthy controls from the United States were randomly divided for training and testing. Images were processed into patches. An XGBoost (

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsAgedHumansMalePancreasRetrospective StudiesTomography, X-Ray ComputedComputer Aided Diagnosis (CAD)Computer Applications-Detection/DiagnosisCTPancreas

Identifiers

PMID34241550
PMCPMC8344348
OpenAlexW3177681144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.