Evidence map›Paper›PMID 34241213›Full record

ArticleThe Journal of chemical physics2021

Mechanical properties of anionic asymmetric bilayers from atomistic simulations.

Wenjuan Jiang, Yi-Chun Lin, Yun Lyna Luo

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The Role of the Swollen State in Cell Proliferation.The Journal of membrane biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wenjuan JiangDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California 91766, USA.ORCID 0000000263603875
Yi-Chun LinDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California 91766, USA.
Yun Lyna LuoDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California 91766, USA.ORCID 000000033581754X

Funding

PHARMACOLOGICAL MODULATION OF PIEZO1 CHANNELSR01GM130834 · NIGMS · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI Yun Lyna LUO, Jerome Lacroix · 2019 to 2026
$2.8M
NIGMS NIH HHS R01 GM130834
6 · The paper itself

Abstract

Mechanotransduction, the biological response to mechanical stress, is often initiated by activation of mechanosensitive (MS) proteins upon mechanically induced deformations of the cell membrane. A current challenge in fully understanding this process is in predicting how lipid bilayers deform upon the application of mechanical stress. In this context, it is now well established that anionic lipids influence the function of many proteins. Here, we test the hypothesis that anionic lipids could indirectly modulate MS proteins by alteration of the lipid bilayer mechanical properties. Using all-atom molecular dynamics simulations, we computed the bilayer bending rigidity (K

Indexed as

AnionsLipid BilayersMechanotransduction, CellularMolecular Dynamics SimulationAnionsLipid Bilayers

Identifiers

PMID34241213
PMCPMC8189722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.