Evidence map›Paper›PMID 34240700›Full record

ArticleeLife2021

Matrix-trapped viruses can prevent invasion of bacterial biofilms by colonizing cells.

Matthew C Bond, Lucia Vidakovic, Praveen K Singh, Knut Drescher, Carey D Nadell

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. The Evolution of Functional Amyloids and Their Impact on Host-Microbe Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  9. Article
  10. Article
  11. Spatial propagation of temperate phages within and among biofilms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Frontiers in microbiology · 2024
    Article
  18. Article
  19. Review
  20. Siphophage 0105phi7-2 ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Matthew C BondDepartment of Biological Sciences, Dartmouth College, Hanover, United States.ORCID 0000-0002-7188-9252
Lucia VidakovicMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0002-5289-5163
Praveen K SinghMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0002-0254-7400
Knut DrescherMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0002-7340-2444
Carey D NadellDepartment of Biological Sciences, Dartmouth College, Hanover, United States.ORCID 0000-0003-1751-4895
Dartmouth College · USMax Planck Institute for Terrestrial Microbiology · DEPhilipps University of Marburg · DE

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEAN R MADDEN · 2018 to 2026
$13.9M
Hypoxia Adaptation and Fungal Virulence of Aspergillus fumigatusR01AI081838 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2009 to 2017
$2.9M
Dartmouth Cystic Fibrosis Training ProgramT32HL134598 · NHLBI · DARTMOUTH COLLEGE · PI George A. O'Toole · 2017 to 2026
$1.7M
NHLBI NIH HHS T32 HL134598NIAID NIH HHS R01 AI081838NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM113132
6 · The paper itself

Abstract

Bacteriophages can be trapped in the matrix of bacterial biofilms, such that the cells inside them are protected. It is not known whether these phages are still infectious and whether they pose a threat to newly arriving bacteria. Here, we address these questions using

Indexed as

BiofilmsBacteriaBacterial Physiological PhenomenaBacteriophagesEscherichia colibacteriophagebiofilmcommunity assemblyE. coliecologyextracellular matrixinvasionspatial ecology

Identifiers

PMID34240700
PMCPMC8346279
OpenAlexW3178728053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.