ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
An MST4-pβ-Catenin
Open access · goldAbstract read
In one paragraph
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- MST4 plays dual roles in lung adenocarcinoma by regulating homeostasis of wild-type and mutant p53 protein.Oncogene · 2026Article
- The MST4-14-3-3ζ complex promotes pancreatic cancer by activating YAP.Biology direct · 2026Article
- Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.Nature communications · 2025Article
- LIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM1.Oncogene · 2025Article
- Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional stress.BMC medicine · 2025Article
- STK26 Promotes the Stabilization of ATF6 to Facilitate the Progression of Colorectal Cancer.International journal of molecular sciences · 2025Article
- CTNNB1 syndrome mouse models.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Review
- Regulatory Mechanism of Intestinal Stem Cells Based on Hippo Pathway and Signaling Crosstalk in Chicken.International journal of molecular sciences · 2025Review
- Targeting STK26 and ATG4B: miR-22-3p as a modulator of autophagy and tumor progression in HCC.Translational oncology · 2025Article
- Genetic Ablation of STE20-Type Kinase MST4 Does Not Alleviate Diet-Induced MASLD Susceptibility in Mice.International journal of molecular sciences · 2024Article
- The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy.Cancer letters · 2023Review
- MST4 promotes proliferation, invasion, and metastasis of gastric cancer by enhancing autophagy.Heliyon · 2023Article
- Review
- Article
- Molecular regulation after mucosal injury and regeneration in ulcerative colitis.Frontiers in molecular biosciences · 2022Review
- Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state.Theranostics · 2022Article
- The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways.International journal of biological sciences · 2022Review
- An MST4-pβ-CateninAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 6 institutions in 2 countries.
Hui ZhangState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Moubin LinDepartment of General Surgery, Yangpu Hospital, Tongji University School of Medicine, Shanghai, 200090, China.
Chao DongDepartment of the Second Medical Oncology, The 3rd Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, 650118, China.
Yang TangDepartment of Medical Ultrasound, Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Liwei AnDepartment of Medical Ultrasound, Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Junyi JuDepartment of Medical Ultrasound, Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Fuping WenState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Fan ChenState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Meng WangState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Wenjia WangState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Min ChenState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Yun ZhaoState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Jixi LiState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Steven X HouState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Xinhua LinState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Lulu HuFudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering and Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College of Fudan University, Shanghai, 200032, China.
Wenbo BuDepartment of Materials Science, Fudan University, Shanghai, 200433, China.
Dianqing WuDepartment of Pharmacology, Yale School of Medicine, New Haven, CT, 06520, USA.
Lin LiState Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Shi JiaoState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Zhaocai ZhouState Key Laboratory of Genetic Engineering, Department of Cell and Developmental Biology, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.ORCID 0000-0002-5441-3922
Fudan University · CNCenter for Excellence in Molecular Cell Science · CNTongji University · CNKunming Medical University · CNShanghai Medical College of Fudan University · CNYale University · US
Funding
DKK2 regulates NK activation and tumor immunityR01CA214703 · NCI · YALE UNIVERSITY · PI WU, DIANQING · 2018 to 2022
$2.5MChina Postdoctoral Science Foundation 2020T130477general projects of basic research in Yunnan Province 2019FB113Key Program for Basic Research of Shanghai 19JC1415600medical discipline leader of Yunnan province D-2019029National Key R&D Program of China 2017YFA0504504National Key R&D Program of China 2020YFA0803200National Natural Science Foundation of China 31930026National Natural Science Foundation of China 81725014National Natural Science Foundation of China 81822035National Natural Science Foundation of China 81874201National Natural Science Foundation of China 82002493National Natural Science Foundation of China 82060542NCI NIH HHS R01 CA214703Open Research Fund of State Key Laboratory of Genetic Engineering, Fudan University SKLGE-2103Shanghai Pujiang Program 19PJ1408300Talent Climbing Project from Shanghai Tenth People's Hospital 2021SYPDRC003top young talents of ten thousand talents plan in Yunnan Province YNWR-QNBJ-2019-275Youth Innovation Promotion Association of the Chinese Academy of Sciences
Abstract
Elevated Wnt/β-catenin signaling has been commonly associated with tumorigenesis especially colorectal cancer (CRC). Here, an MST4-pβ-catenin
Indexed as
Animalsbeta CateninCarcinogenesisColorectal NeoplasmsDisease Models, AnimalFemaleHippo KinasesHumansIntestinesMaleMiceMice, Inbred BALB CMice, Inbred C57BLProtein Serine-Threonine KinasesStem CellsWnt Signaling Pathwaybeta CateninHippo KinasesProtein Serine-Threonine KinasesSTK26 protein, humanStk26 protein, mousecancer stem cellscolorectal cancerintestinal stem cellsMST4-pβ-cateninThr40 signaling axistargeted therapy
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.