Evidence map›Paper›PMID 34240548›Full record

ArticleJournal of applied clinical medical physics2021

Technical Note: Volumetric computed tomography for radiotherapy simulation and treatment planning.

Heather M Young, Claire Keun Sun Park, Oi-Wai Chau, Ting-Yim Lee, Stewart Gaede

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Heather M YoungDepartment of Medical Biophysics, University of Western Ontario, London, Canada.
Claire Keun Sun ParkDepartment of Medical Biophysics, University of Western Ontario, London, Canada.
Oi-Wai ChauDepartment of Medical Biophysics, University of Western Ontario, London, Canada.
Ting-Yim LeeDepartment of Medical Biophysics, University of Western Ontario, London, Canada.
Stewart GaedeDepartment of Medical Biophysics, University of Western Ontario, London, Canada.
Western University · CA

Funding

Lawson Health Research InstituteNatural Sciences and Engineering Research Council of Canada
6 · The paper itself

Abstract

purposeFor lung and liver tumors requiring radiotherapy, motion artifacts are common in 4D-CT images due to the small axial field-of-view (aFOV) of conventional CT scanners. This may negatively impact contouring and dose calculation accuracy and could lead to a geographic miss during treatment. Recent advancements in volumetric CT (vCT) enable an aFOV up to 160 mm in a single rotation, which may reduce motion artifacts. However, the impact of large aFOV on CT number required for dose calculation needs to be evaluated before clinical implementation. The objective of this study was to determine the utility of a 256-slice vCT scanner for 4D-CT simulation by evaluating image quality and generating relative electron density (RED) curves.

methodsImages were acquired on a 256-slice GE Revolution CT scanner with 40 mm, 80 mm, 120 mm, 140 mm, and 160 mm aFOV. Image quality was assessed by evaluating CT number linearity, uniformity, noise, and low-contrast resolution. The relationship between each quality metric and aFOV was assessed.

resultsCT number linearity, uniformity, noise, and low-contrast resolution were within the expected range for each image set, except CT number in Teflon and Delrin, which were underestimated. Spearman correlation coefficient (ρ) showed that the CT number for Teflon (ρ = 1.0, p = 0.02), Delrin (ρ = 1.0, p = 0.02), and air (ρ = 1.0, p = 0.02) was significantly related to aFOV, while all other measurements were not. The measured deviations from expected values were not clinically significant.

conclusionThese results suggest that vCT can be used for CT simulation for radiation treatment planning.

Indexed as

Cone-Beam Computed TomographyRadiation OncologyComputer SimulationHumansPhantoms, ImagingRadiotherapy DosageTomography Scanners, X-Ray Computedradiation treatment planningradiotherapy simulationvolumetric computed tomography

Identifiers

PMID34240548
PMCPMC8364284
OpenAlexW3182216805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.