Evidence map›Paper›PMID 34240439›Full record

ArticlePacing and clinical electrophysiology : PACE2021

Prevalence of bradyarrhythmias needing pacing in COVID-19.

Zaki Akhtar, Lisa Wm Leung, Christos Kontogiannis, Zia Zuberi, Abhay Bajpai, Sumeet Sharma, Zhong Chen, Ian Beeton, Manav Sohal, Mark M Gallagher

Open access · bronzeAbstract read
In one paragraph

Article in Pacing and clinical electrophysiology : PACE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Effects of COVID-19 on Arrhythmia.Journal of cardiovascular development and disease · 2022
    Review
  11. Medium-Term Outcomes in COVID-19.Journal of clinical medicine · 2022
    Article
  12. Article
  13. COVID-19 and Cardiac Arrhythmias: a Contemporary Review.Current treatment options in cardiovascular medicine · 2022
    Review
  14. Prevalence of bradyarrhythmias needing pacing in COVID-19.Pacing and clinical electrophysiology : PACE · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zaki AkhtarCardiology, St George's University Hospital NHS trust, London, UK.
Lisa Wm LeungCardiology, St George's University Hospital NHS trust, London, UK.
Christos KontogiannisCardiology, St George's University Hospital NHS trust, London, UK.ORCID 0000-0001-7485-6440
Zia ZuberiCardiology, St George's University Hospital NHS trust, London, UK.
Abhay BajpaiCardiology, St George's University Hospital NHS trust, London, UK.
Sumeet SharmaCardiology, St George's University Hospital NHS trust, London, UK.
Zhong ChenCardiology, Ashford and St Peter's Hospitals NHS trust, Surrey, UK.
Ian BeetonCardiology, Ashford and St Peter's Hospitals NHS trust, Surrey, UK.
Manav SohalCardiology, St George's University Hospital NHS trust, London, UK.
Mark M GallagherCardiology, St George's University Hospital NHS trust, London, UK.ORCID 0000-0002-6333-6420
St George’s University Hospitals NHS Foundation Trust · GBSt Peter's Hospital · GBRoyal Surrey County Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Sars-Cov-2 infection is a multisystem illness that can affect the cardiovascular system. Tachyarrhythmias have been reported but the prevalence of bradyarrhythmia is unclear. Cases have been described of transient high-degree atrioventricular (AV) block in COVID-19 that were managed conservatively.

methodA database of all patients requiring temporary or permanent pacing in two linked cardiac centers was used to compare the number of procedures required during the first year of the pandemic compared to the corresponding period a year earlier. The database was cross-referenced with a database of all patients testing positive for Sars-Cov-2 infection in both institutions to identify patients who required temporary or permanent pacing during COVID-19.

resultsThe number of novel pacemaker implants was lower during the COVID-19 pandemic than the same period the previous year (540 vs. 629, respectively), with a similar proportion of high-degree AV block (38.3% vs. 33.2%, respectively, p = .069). Four patients with the Sars-Cov-2 infection had a pacemaker implanted for high-degree AV block, two for sinus node dysfunction. Of this cohort of six patients, two succumbed to the COVID-19 illness and one from non-COVID sepsis. Device interrogation demonstrated a sustained pacing requirement in all cases.

conclusionHigh-degree AV block remained unaltered in prevalence during the COVID-19 pandemic. There was no evidence of transient high-degree AV block in patients with the Sars-Cov-2 infection. Our experience suggests that all clinically significant bradyarrhythmia should be treated by pacing according to usual protocols regardless of the COVID status.

Indexed as

Cardiac Pacing, ArtificialAgedAged, 80 and overBradycardiaCOVID-19HumansMalePrevalencebradycardiaCOVID-19high-degree AV blockpacing

Identifiers

PMID34240439
PMCPMC8447422
OpenAlexW3181447863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.