Evidence map›Paper›PMID 34240333›Full record

ArticleGeroScience2021

San Antonio Nathan Shock Center: your one-stop shop for aging research.

Adam B Salmon, James F Nelson, Jonathan A L Gelfond, Martin Javors, Brett Ginsburg, Marisa Lopez-Cruzan, Veronica Galvan, Elizabeth Fernandez, Nicolas Musi, Yuji Ikeno and 4 more

Abstract read
In one paragraph

Article in GeroScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adam B SalmonBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
James F NelsonBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Jonathan A L GelfondBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Martin JavorsBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Brett GinsburgBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Marisa Lopez-CruzanBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Veronica GalvanBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Elizabeth FernandezBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Nicolas MusiBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Yuji IkenoBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Gene HubbardBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
James LechleiterBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Peter J HornsbyBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Randy StrongBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, 78229, USA. strong@uthscsa.edu.

Funding

TRANSGENIC COREP30AG013319 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JAMES FLOYD NELSON · 1995 to 2026
$30.6M
Targeting Cellular Senescence to Extend HealthspanP01AG062413 · NIA · MAYO CLINIC ROCHESTER · PI Sundeep Khosla, Nathan K LeBrasseur · 2019 to 2026
$28.7M
Reduced thioredoxin in both the cytosol and mitochondria: a key modulator of age-related cancer development in Trx1KO x Trx2KO mice?R01AG070034 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IKENO, YUJI · 2021 to 2025
$2.0M
NIA NIH HHS P01 AG062413NIA NIH HHS P30 AG013319NIA NIH HHS R01 AG070034
6 · The paper itself

Abstract

With evolving cores, enrichment and training programs, and supported research projects, the San Antonio (SA) Nathan Shock Center has for 26 years provided critical support to investigators locally, nationally, and abroad. With its existing and growing intellectual capital, the SA Nathan Shock Center provides to local and external investigators an enhanced platform to conduct horizontally integrated (lifespan, healthspan, pathology, pharmacology) transformative research in the biology of aging, and serves as a springboard for advanced educational and training activities in aging research. The SA Nathan Shock Center consists of six cores: Administrative/Program Enrichment Core, Research Development Core, Aging Animal Models and Longevity Assessment Core, Pathology Core, Analytical Pharmacology and Drug Evaluation Core, and Integrated Physiology of Aging Core. The overarching goal of the SA Nathan Shock Center is to advance knowledge in the basic biology of aging and to identify molecular and cellular mechanisms that will facilitate the development of pharmacologic interventions and other strategies to extend healthy lifespan. In pursuit of this goal, we provide an innovative "one-stop shop" venue to accelerate transformative research in the biology of aging through our integrated research cores. Moreover, we aim to foster and promote career development of early-stage investigators in aging biology through our research development programs, to serve as a resource and partner to investigators from other Shock Centers, and to disseminate scientific knowledge and enhanced awareness about aging research. Overall, the SA Nathan Shock Center aims to be a leader in research that advances our understanding of the biology of aging and development of approaches to improve longevity and healthy aging.

Indexed as

GeroscienceHealthy AgingAgingAnimalsLongevityBiostatisticsLongevityPathologyPharmacologyPhysiologyPilot grants

Identifiers

PMID34240333
PMCPMC8599539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.