ArticleThe Plant cell2021
GmPIN-dependent polar auxin transport is involved in soybean nodule development.
Article in The Plant cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 59 citations in OpenAlex.
- Review
- Spatiotemporal Metabolome and Single-Nucleus Transcriptome Integration Illuminates an Auxin Gradient Orchestrated by NtTAC1 Underlying Leaf Angle Regulation in Tobacco.Plant biotechnology journal · 2026Article
- Unearthing Root Response Mechanisms to Soil Compaction in Legumes.Plant, cell & environment · 2026Review
- Role of theHorticulture research · 2026Article
- Evolutionary Repurposing of Cytokinin Signaling in Plant Development and Symbiosis.Plants (Basel, Switzerland) · 2026Review
- Identification of symbiotic nitrogen fixation-modulating factors in alfalfa and mechanism elucidation of MsHHO3.The Plant journal : for cell and molecular biology · 2026Article
- Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Challenges and Opportunities with CRISPR-Based Genome Editing in Legume Crops.Functional & integrative genomics · 2026Review
- Coordination of cortex modifications in time, space, and under stress.The New phytologist · 2025Review
- pMAGs: A Versatile and Efficient Vector System for Multi-Gene Studies in Plants.Plants (Basel, Switzerland) · 2025Article
- Regulatory Mechanism of the GmMYB14 Transcription Factor on Auxin-Related Proteins in Soybean.International journal of molecular sciences · 2025Article
- CRISPR/Cas genome editing in soybean: challenges and new insights to overcome existing bottlenecks.Journal of advanced research · 2025Review
- Nodule organogenesis in Medicago truncatula requires local stage-specific auxin biosynthesis and transport.Plant physiology · 2025Article
- Yield and yield component trait analysis with DArT genotyping for GWAS in soybean grown in drought conditions of Kazakhstan.Frontiers in plant science · 2025Article
- Genome-wide identification and expression analysis of soybean bHLH transcription factor and its molecular mechanism on grain protein synthesis.Frontiers in plant science · 2025Article
- Advancing PAM-less genome editing in soybean using CRISPR-SpRY.Horticulture research · 2024Article
- Mapping the molecular landscape of Lotus japonicus nodule organogenesis through spatiotemporal transcriptomics.Nature communications · 2024Article
- UnregulatedInternational journal of molecular sciences · 2024Article
- Effect of aFrontiers in plant science · 2024Article
- Biosynthesis and metabolic engineering of isoflavonoids in model plants and crops: a review.Frontiers in plant science · 2024Review
Corrections and comments
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Authors and funding
21 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To overcome nitrogen deficiency, legume roots establish symbiotic interactions with nitrogen-fixing rhizobia that are fostered in specialized organs (nodules). Similar to other organs, nodule formation is determined by a local maximum of the phytohormone auxin at the primordium site. However, how auxin regulates nodule development remains poorly understood. Here, we found that in soybean, (Glycine max), dynamic auxin transport driven by PIN-FORMED (PIN) transporter GmPIN1 is involved in nodule primordium formation. GmPIN1 was specifically expressed in nodule primordium cells and GmPIN1 was polarly localized in these cells. Two nodulation regulators, (iso)flavonoids trigger expanded distribution of GmPIN1b to root cortical cells, and cytokinin rearranges GmPIN1b polarity. Gmpin1abc triple mutants generated with CRISPR-Cas9 showed the impaired establishment of auxin maxima in nodule meristems and aberrant divisions in the nodule primordium cells. Moreover, overexpression of GmPIN1 suppressed nodule primordium initiation. GmPIN9d, an ortholog of Arabidopsis thaliana PIN2, acts together with GmPIN1 later in nodule development to acropetally transport auxin in vascular bundles, fine-tuning the auxin supply for nodule enlargement. Our findings reveal how PIN-dependent auxin transport modulates different aspects of soybean nodule development and suggest that the establishment of auxin gradient is a prerequisite for the proper interaction between legumes and rhizobia.
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