ReviewThe Plant cell2021
The sequenced genomes of nonflowering land plants reveal the innovative evolutionary history of peptide signaling.
Review in The Plant cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 61 citations in OpenAlex.
- The Sulfated PSY Peptide Negatively Regulates Receptor Kinase Activity to Promote Growth.bioRxiv : the preprint server for biology · 2026Article
- An LRR co-receptor kinase essential for systemic nitrogen-demand signalling.Nature plants · 2026Article
- Article
- Evolutionary shifts in plant adaptation mediated by phytohormones.Plant communications · 2026Review
- Structural basis for the activation of an LRR receptor by a single-disulfide-bridged peptide signal.Plant communications · 2026Article
- Pan-eukaryotic distribution and deep homology of plant small secreted peptides and their receptors.iScience · 2026Article
- Plant cell surface receptors.The Plant journal : for cell and molecular biology · 2026Review
- The 'non-conventional' peptidome: A new layer in plant regulatory mechanisms.Plant communications · 2025Review
- CEPR1 function across plant lineages: peptide hormone recognition by cereal crop orthologs and developmental roles in barley.Journal of experimental botany · 2025Article
- CLE pathways in plant development: recent advances and future perspectives.Journal of experimental botany · 2025Review
- Evidence for Early Evolution of Sulfated Peptide Signaling in Plant Development.bioRxiv : the preprint server for biology · 2025Article
- Time-resolved oxidative signal convergence across the algae-embryophyte divide.Nature communications · 2025Article
- Peptide hormones in plants.Molecular horticulture · 2025Review
- The rise of CLAVATA: evidence for CLAVATA3 and WOX signaling in the fern gametophyte.The Plant journal : for cell and molecular biology · 2025Article
- CEP signaling coordinates plant immunity with nitrogen status.Nature communications · 2024Article
- Macromolecular tool box to elucidate CLAVATA3/EMBRYO SURROUNDING REGION-RELATED-RLK binding, signaling, and downstream effects.Journal of experimental botany · 2024Article
- Leveraging coevolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Evolutionary conservation of receptor compensation for stem cell homeostasis in Solanaceae plants.Horticulture research · 2024Article
- CEP hormones at the nexus of nutrient acquisition and allocation, root development, and plant-microbe interactions.Journal of experimental botany · 2024Review
- Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An understanding of land plant evolution is a prerequisite for in-depth knowledge of plant biology. Here we extract and explore information hidden in the increasing number of sequenced plant genomes, from bryophytes to angiosperms, to elucidate a specific biological question-how peptide signaling evolved. To conquer land and cope with changing environmental conditions, plants have gone through transformations that must have required innovations in cell-to-cell communication. We discuss peptides mediating endogenous and exogenous changes by interaction with receptors activating intracellular molecular signaling. Signaling peptides were discovered in angiosperms and operate in tissues and organs such as flowers, seeds, vasculature, and 3D meristems that are not universally conserved across land plants. Nevertheless, orthologs of angiosperm peptides and receptors have been identified in nonangiosperms. These discoveries provoke questions regarding coevolution of ligands and their receptors, and whether de novo interactions in peptide signaling pathways may have contributed to generate novel traits in land plants. The answers to such questions will have profound implications for the understanding of the evolution of cell-to-cell communication and the wealth of diversified terrestrial plants. Under this perspective, we have generated, analyzed, and reviewed phylogenetic, genomic, structural, and functional data to elucidate the evolution of peptide signaling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.