Evidence map›Paper›PMID 34240077›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2021

Surgical Treatment and Outcomes of Colorectal Cancer Patients During the COVID-19 Pandemic: A National Population-based Study in England.

Angela Kuryba, Jemma M Boyle, Helen A Blake, Ajay Aggarwal, Jan van der Meulen, Michael Braun, Kate Walker, Nicola S Fearnhead

Open access · goldAbstract read
In one paragraph

Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. COVID-19 on Elective Surgery Outcomes in a Brazilian Tertiary Hospital: A Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
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  15. Surgical safety in the COVID-19 era: present and future considerations.Annals of surgical treatment and research · 2022
    Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Colorectal cancer care in the COVID-19 era: outcomes from a 'mixed site' model.Annals of the Royal College of Surgeons of England · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Angela KurybaClinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom.
Jemma M BoyleClinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom.
Helen A BlakeClinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom.
Ajay AggarwalDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Jan van der MeulenClinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom.
Michael BraunDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Kate WalkerClinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom.
Nicola S FearnheadDepartment of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Royal College of Surgeons of England · GBLondon School of Hygiene & Tropical Medicine · GBCambridge University Hospitals NHS Foundation Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBThe Christie NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the management and outcomes of colorectal cancer (CRC) patients during the first 2 months of the COVID-19 pandemic with the preceding 6 months.

backgroundThe pandemic has affected the diagnosis and treatment of CRC patients worldwide. Little is known about the safety of major resection and whether creating "cold" sites (COVID-free hospitals) is effective.

methodsA national study in England used administrative hospital data for 14,930 CRC patients undergoing surgery between October 1, 2019, and May 31, 2020. Mortality of CRC resection was compared before and after March 23, 2020 ("lockdown" start).

resultsThe number of elective CRC procedures dropped sharply during the pandemic (from average 386 to 214 per week), whereas emergency procedures were hardly affected (from 88 to 84 per week). There was little change in characteristics of surgical patients during the pandemic. Laparoscopic surgery decreased from 62.5% to 35.9% for elective and from 17.7% to 9.7% for emergency resections. Surgical mortality increased slightly (from 0.9% to 1.2%,

conclusionsThe pandemic resulted in a 50% reduction in elective CRC procedures during the initial surge and a substantial increase in mortality after emergency resection. There was no evidence that surgery in COVID-free "cold" sites led to better outcomes in the first 2 months.

Indexed as

colorectal cancerCOVID-19surgical mortality

Identifiers

PMID34240077
PMCPMC8223908
OpenAlexW3168723222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.