Evidence map›Paper›PMID 34239929›Full record

ArticleBioMed research international2021

Stereological Study of Changes of GABA-Immunoreactive Neurons in Spinal Dorsal Horn of SNI Rats.

Hong Liu, Weidong Li, Binbing Xu, Jiduan Jiang, Yuanyuan Zhang, Fan Yang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hong LiuDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0001-6534-9113
Weidong LiDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0002-7171-0697
Binbing XuDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0002-9427-8964
Jiduan JiangDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0002-7402-5599
Yuanyuan ZhangDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0002-8494-8821
Fan YangDepartment of Anesthesiology, Suining Central Hospital, Suining 629000, Sichuan Province, China.ORCID https://orcid.org/0000-0003-4392-9090
Suizhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the changes in the mechanical withdrawal threshold (MWT) and the proportion of GABA-immunoreactive neurons in spinal dorsal horn (SDH) of the spared nerve injury (SNI) rat model.

methodsThirty-six healthy male SD rats were randomly divided into a sham-operated group (group D,

resultsIn group S, compared with the baseline measured 1 day before surgery, MWT on the medial and lateral sides of the rats' left hindpaw decreased significantly on the 7

conclusionThe SNI model could reduce the proportion of GABA-immunoreactive neurons in the rat's spinal dorsal horn on the nerve-injured side, and this change was lasting, which might be related to the transformation of the GABA-immunoreactive neurons.

Indexed as

AnimalsBody WeightGABAergic Neuronsgamma-Aminobutyric AcidImmune SystemMaleNeuralgiaNeurotransmitter AgentsPosterior Horn CellsRatsRats, Sprague-DawleySciatic NerveSpinal Cord Dorsal HornStress, Mechanicalgamma-Aminobutyric AcidNeurotransmitter Agents

Identifiers

PMID34239929
PMCPMC8233084
OpenAlexW3174469713

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.