Evidence map›Paper›PMID 34239907›Full record

ArticleFrontiers in cardiovascular medicine2021

Higher Serum Cholesterol Levels Are Associated With Reduced Systemic Inflammation and Mortality During Tuberculosis Treatment Independent of Body Mass Index.

Vignesh Chidambaram, Lucas Zhou, Jennie Ruelas Castillo, Amudha Kumar, Samuel K Ayeh, Akshay Gupte, Jann-Yuan Wang, Petros C Karakousis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Low Cholesterol Associated With TB in People Living With HIV in an Asia-Pacific Cohort.Journal of acquired immune deficiency syndromes (1999) · 2026
    Article
  7. Review
  8. Reactivation ofCase reports in infectious diseases · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Association between Dyslipidemia and Pulmonary Diseases.Journal of atherosclerosis and thrombosis · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Vignesh ChidambaramDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Lucas ZhouDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Jennie Ruelas CastilloDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Amudha KumarDepartment of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Samuel K AyehDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Akshay GupteDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Jann-Yuan WangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Petros C KarakousisDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Johns Hopkins Medicine · USJohns Hopkins University · USNational Taiwan University Hospital · TWUniversity of Arkansas for Medical Sciences · US

Funding

Statins as Adjunctive, Host-Directed Therapy for TBUH3AI122309 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KARAKOUSIS, PETROS C · 2017 to 2019
$4.3M
Mentoring in Immunometabolic Dysregulation in TB and TB/HIVK24AI143447 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KARAKOUSIS, PETROS C · 2019 to 2024
$956k
NIAID NIH HHS K24 AI143447NIAID NIH HHS UH3 AI122309
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BMIeffect modificationHDL-cholesterolinflammationLDL-cholesterol

Identifiers

PMID34239907
PMCPMC8257940
OpenAlexW3174797672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.