Evidence map›Paper›PMID 34239869›Full record

ReviewFrontiers in cell and developmental biology2021

Emerging Potential of Exosomes on Adipogenic Differentiation of Mesenchymal Stem Cells.

Yuxuan Zhong, Xiang Li, Fanglin Wang, Shoushuai Wang, Xiaohong Wang, Xiaohong Tian, Shuling Bai, Di Miao, Jun Fan

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  6. Review
  7. Article
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  9. Article
  10. Review
  11. Article
  12. Article
  13. The emerging roles of exosomal long non-coding RNAs in bladder cancer.Journal of cellular and molecular medicine · 2022
    Review
  14. Exosome mediated biological functions within skeletal microenvironment.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yuxuan ZhongDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Xiang LiDepartment of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang, China.
Fanglin WangDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Shoushuai WangDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Xiaohong WangDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Xiaohong TianDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Shuling BaiDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
Di MiaoChina Medical University-The Queen's University of Belfast Joint College-Combination, Shenyang, China.
Jun FanDepartment of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, China.
China Medical University · CNQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mesenchymal stem cells have multidirectional differentiation potential and can differentiate into adipocytes, osteoblasts, cartilage tissue, muscle cells and so on. The adipogenic differentiation of mesenchymal stem cells is of great significance for the construction of tissue-engineered fat and the treatment of soft tissue defects. Exosomes are nanoscale vesicles secreted by cells and widely exist in body fluids. They are mainly involved in cell communication processes and transferring cargo contents to recipient cells. In addition, exosomes can also promote tissue and organ regeneration. Recent studies have shown that various exosomes can influence the adipogenic differentiation of stem cells. In this review, the effects of exosomes on stem cell differentiation, especially on adipogenic differentiation, will be discussed, and the mechanisms and conclusions will be drawn. The main purpose of studying the role of these exosomes is to understand more comprehensively the influencing factors existing in the process of stem cell differentiation into adipocytes and provide a new idea in adipose tissue engineering research.

Indexed as

adipogenesisadipogenic differentiationexosomesmesenchymal stem cellregenerative medicine

Identifiers

PMID34239869
PMCPMC8258133
OpenAlexW3176176247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.