Evidence map›Paper›PMID 34239791›Full record

ArticleCureus2021

Scoliosis and Gastroesophageal Reflux Disease in Adults.

Fahri Eryilmaz, Faheem Ahmed, Asim K Rehmani, Sundas Karimi, Aamna Qazi, Sufyan Mustafa, Arif Zulfiqar, Zubia Nadeem, Ayyaz A Sultan, Umar Farooque

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Fahri EryilmazNeurological Surgery, Hitit University Corum Erol Olcok Training and Research Hospital, Corum, TUR.
Faheem AhmedOrthopedic Surgery, Trauma Centre, Civil Hospital, Karachi, PAK.
Asim K RehmaniNeurological Surgery, National Medical Center, Karachi, PAK.
Sundas KarimiOrthopedic Surgery, Dow University Hospital, Karachi, PAK.
Aamna QaziMedicine, Dow University of Health Sciences, Karachi, PAK.
Sufyan MustafaMedicine, Dow Medical College, Civil Hospital, Karachi, PAK.
Arif ZulfiqarMedicine and Surgery, Dow Medical College, Karachi, PAK.
Zubia NadeemMedicine, Dow University of Health Sciences, Karachi, PAK.
Ayyaz A SultanHematology/Oncology, California Cancer Associates for Research and Excellence, Fresno, USA.
Umar FarooqueNeurology, Dow University of Health Sciences, Karachi, PAK.
Hitit Üniversitesi · TRCivil Hospital Karachi · PKCalifornia Cancer Associates for Research and Excellence · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Degenerative scoliosis most commonly presents with lower back pain. Literature suggests that adults who have degenerative scoliosis are at greater risk of both hiatal hernia and gastroesophageal reflux disease (GERD). The objective of this study was to evaluate scoliosis as being the risk factor of GERD in adults. Materials and methods This prospective study was conducted at Dow University of Health Sciences over a period of two years (May 2018 to April 2020). The investigation included 210 participants with spinal disorders. The mean age was 71.6±9.6 years. The X-rays of the participants' whole spine were taken in a standing position, in the sagittal and coronal planes. Symptoms of GERD were measured through the quality of life and utility evaluation survey technology (QUEST) score, taking six points as cutoff values. The evaluation was done using radiographs to determine any relationship between spinal disorders and GERD. Negative values were analyzed in a right-sided convex curve while positive values in the left-sided convex curve were viewed in the coronal plane. Degenerative scoliosis was explained as a lumbar/thoracolumbar Cobb angle of more than 10 degrees. Univariate and multivariate logistic regression analyses were done to assess the risk factors related to GERD. Results Out of 210 patients, 146 were found to have degenerative scoliosis at the level of the lumbar and thoracolumbar spine. Fifty-two patients had a right convex curve, and 94 had a left convex curve. Sixty-nine patients had GERD. According to the analysis of the multivariate logistic regression, the Cobb angle was highly related to GERD (p-value <0.05 and odds ratio of 1.031). The participants were grouped according to the Cobb angle of curve at the lumbar spine (less than 30 degrees with a large right-sided convex curve, 30 and more with a small curve, and more than 30+ degrees with a large left-sided convex curve). The study revealed that a large left-sided convex curve was highly related to GERD, with a p-value <0.05 and odds ratio of 10.935. Conclusions The left-sided large convex curve at the thoracolumbar or lumbar spine, especially when the Cobb angle was more than 30 degrees, was highly associated with GERD. Therefore, the symptoms of GERD should be monitored in the elderly population with degenerative scoliosis.

Indexed as

cobb anglegastroesophageal reflux diseasequest scoresagittal planescoliosis

Identifiers

PMID34239791
PMCPMC8245622
OpenAlexW3168980055

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.