Evidence map›Paper›PMID 34239571›Full record

ArticleInternational journal of biomaterials2021

Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model.

Benedict Lotz, Friederike Bothe, Anne-Kathrin Deubel, Eliane Hesse, Yvonne Renz, Carsten Werner, Simone Schäfer, Thomas Böck, Jürgen Groll, Brigitte von Rechenberg and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Benedict LotzCenter of Orthopaedic and Trauma Surgery/Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.ORCID https://orcid.org/0000-0001-7883-8696
Friederike BotheResearch Center for Experimental Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.ORCID https://orcid.org/0000-0001-9406-415X
Anne-Kathrin DeubelResearch Center for Experimental Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.
Eliane HesseResearch Center for Experimental Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.
Yvonne RenzResearch Center for Experimental Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.
Carsten WernerLeibniz Institute of Polymer Research Dresden, Hohe Straße 6, Dresden 01069, Germany.
Simone SchäferChair of Functional Materials in Medicine and Dentistry and Bavarian Polymer Institute, University of Würzburg, Pleicherwall 2, Würzburg 97070, Germany.
Thomas BöckChair of Functional Materials in Medicine and Dentistry and Bavarian Polymer Institute, University of Würzburg, Pleicherwall 2, Würzburg 97070, Germany.
Jürgen GrollChair of Functional Materials in Medicine and Dentistry and Bavarian Polymer Institute, University of Würzburg, Pleicherwall 2, Würzburg 97070, Germany.
Brigitte von RechenbergMusculoskeletal Research Unit (MSRU) Center for Applied Biotechnology and Molecular Medicine (CABMM), University Zürich, Winterthurerstraße 190, CH-8057 Zürich, Switzerland.
Wiltrud RichterResearch Center for Experimental Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.
Sebastien HagmannCenter of Orthopaedic and Trauma Surgery/Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstraße 200a, Heidelberg 69118, Germany.ORCID https://orcid.org/0000-0003-1671-2494
Heidelberg University · DEUniversity of Würzburg · DELeibniz Institute of Polymer Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reinforced hydrogels represent a promising strategy for tissue engineering of articular cartilage. They can recreate mechanical and biological characteristics of native articular cartilage and promote cartilage regeneration in combination with mesenchymal stromal cells. One of the limitations of

Identifiers

PMID34239571
PMCPMC8235960
OpenAlexW3175191219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.