Evidence map›Paper›PMID 34239566›Full record

ArticleJournal of oncology2021

Prognostic Value of Albumin to D-Dimer Ratio in Advanced Gastric Cancer.

Liqun Zhang, Zhuo Wang, Jiawen Xiao, Zhiyan Zhang, Haijing Li, Fang Li, Lisha Zhang, Yuanhe Wang

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Pre-Chemotherapy D-Dimer Levels as Predictors of Survival Outcomes in Advanced Gastric Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Liqun ZhangDepartment of Medical Oncology, Shenyang Fifth People Hospital, Tiexi District, Shenyang 110020, Liaoning Province, China.ORCID https://orcid.org/0000-0002-4206-5596
Zhuo WangDepartment of Medical Oncology, Liaohua Hospital, Hongwei District, Liaoyang 111003, Liaoning Province, China.
Jiawen XiaoDepartment of Medical Oncology, Shenyang Fifth People Hospital, Tiexi District, Shenyang 110020, Liaoning Province, China.
Zhiyan ZhangDepartment of Medical Oncology, Shenyang Fifth People Hospital, Tiexi District, Shenyang 110020, Liaoning Province, China.
Haijing LiDepartment of Medical Oncology, Shenyang Fifth People Hospital, Tiexi District, Shenyang 110020, Liaoning Province, China.
Fang LiDepartment of Hepatobiliary Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University, No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Lisha ZhangDepartment of Gastrointestinal Surgery, The Second Hospital Affiliated to Harbin Medical University, No. 246, Xuefu Road, Nangang District, Harbin 150086, Heilongjiang Province, China.
Yuanhe WangMedical Oncology Department of Gastrointestinal Cancer, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University, No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.ORCID https://orcid.org/0000-0002-0012-1756
Shenyang Fifth People Hospital · CNHarbin Medical University · CNLiaoning Cancer Hospital & Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is one of the most common malignancies worldwide. Notably, patients with advanced GC have a poor prognosis and quality of life, prompting the need for further studies on its prognostic markers. Among these, albumin and D-dimer are often used as prognostic factors in the prediction of a variety of tumors. Moreover, the albumin to D-dimer ratio (ADR) may be an improved predictor of chemotherapy effect and survival compared to albumin and D-dimer alone, but few studies have investigated this issue. Thus, we explored the relationship between pretreatment ADR and prognosis in advanced GC treated with first-line chemotherapy. A total of 247 advanced unresectable GC patients treated with first-line chemotherapy were retrospectively included. The cut-off value for ADR was determined using the receiver operating characteristic (ROC) curve. The ADR had a cut-off value of 41.64. Compared to albumin and D-dimer alone, ADR had the highest area under curve (AUC) value (AUC = 0.730), followed by albumin (AUC = 0.659) and D-dimer (AUC = 0.719). Additionally, we found that patients with a low ADR (<41.64) had a lower disease control rate (77.9% vs. 92.5%,

Identifiers

PMID34239566
PMCPMC8241521
OpenAlexW3175569064

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.