Evidence map›Paper›PMID 34239352›Full record

ArticleInternational journal of biological sciences2021

Inhibition of

Thuy Phan, Vu H Nguyen, Ralf Buettner, Corey Morales, Lifeng Yang, Paul Wong, Weiman Tsai, Marcela d'Alincourt Salazar, Ziv Gil, Don J Diamond and 3 more

Abstract read
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Thuy PhanDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010.
Vu H NguyenDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Ralf BuettnerDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Corey MoralesDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Lifeng YangLewis Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, NJ 08544.
Paul WongDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010.
Weiman TsaiDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Marcela d'Alincourt SalazarDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Ziv GilRambam Medical Center, Israel.
Don J DiamondDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Joshua D RabinowitzLewis Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, NJ 08544.
Steven RosenDepartment of Hematology, City of Hope National Medical Center, Duarte, CA 91010.
Laleh G MelstromDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leflunomide (Lef) is an agent used in autoimmune disorders that interferes with DNA synthesis.

Indexed as

AnimalsAntimetabolites, AntineoplasticApoptosisCell Line, TumorCell ProliferationDeoxycytidineDisease Models, AnimalFemaleGemcitabineImmunocompetenceKi-67 AntigenMiceMice, Inbred C57BLPancreatic NeoplasmsTumor MicroenvironmentAntimetabolites, AntineoplasticDeoxycytidineGemcitabineKi-67 AntigenMKI67 protein, humande novo pyrimidine synthesisleflunomidepancreatic cancer

Identifiers

PMID34239352
PMCPMC8241727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.