ArticleInternational journal of biological sciences2021
Hexokinase 3 dysfunction promotes tumorigenesis and immune escape by upregulating monocyte/macrophage infiltration into the clear cell renal cell carcinoma microenvironment.
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Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
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Who cites it
48 citing papers in PubMed, 63 citations in OpenAlex.
- Post-translational modifications in metabolic reprogramming: implications for metabolic therapy and immunotherapy in cancer.Signal transduction and targeted therapy · 2026Review
- Effects of FGF4/HIF-1α axis-mediated neuronal glycolysis on neuropathic pain.The journal of headache and pain · 2026Article
- Hyperinsulinemia in Sotos Syndrome with aJournal of clinical research in pediatric endocrinology · 2026Article
- Obesity-driven metabolic reprogramming and immune dysfunction in renal cancer.Frontiers in immunology · 2026Review
- Noninvasive Prediction of Programmed Cell Death Protein-Ligand 1 Expression in Locally Advanced Non-small Cell Lung Cancer byAnnals of surgical oncology · 2025Article
- Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors.Nature reviews. Nephrology · 2025Review
- Proteomics and succinylation modification characterization in clear cell renal cell carcinoma.Discover oncology · 2025Article
- Multi-omics analysis reveals immunosuppression in oesophageal squamous cell carcinoma induced by creatine accumulation and HK3 deficiency.Genome medicine · 2025Article
- Reliable hexokinase 3 protein detection in human cell lines and primary tissue.European journal of histochemistry : EJH · 2025Article
- Emerging roles of metabolic biomarkers in renal cell carcinoma: from molecular mechanisms to clinical implications.Frontiers in cell and developmental biology · 2025Review
- Multiomics Approach Distinguishes SPTBN4 as a Key Molecule in Diagnosis, Prognosis, and Immune Suppression of Testicular Seminomas.International journal of genomics · 2025Article
- Heterogeneity of Neutrophils and Immunological Function in Neonatal Sepsis: Analysis of Molecular Subtypes Based on Hypoxia-Glycolysis-Lactylation.Mediators of inflammation · 2025Article
- TCF3 as a multidimensional biomarker: oncogenicity, genomic alterations, and immune landscape in pan-cancer analysis.Acta biochimica et biophysica Sinica · 2024Article
- Hexokinase HK3-mediated O-GlcNAcylation of EP300: a key regulator of PD-L1 expression and immune evasion in ccRCC.Cell death & disease · 2024Article
- PD1/PD-L1 blockade in clear cell renal cell carcinoma: mechanistic insights, clinical efficacy, and future perspectives.Molecular cancer · 2024Review
- Metabolic alterations in hereditary and sporadic renal cell carcinoma.Nature reviews. Nephrology · 2024Review
- Unveiling the impact of tertiary lymphoid structures on immunotherapeutic responses of clear cell renal cell carcinoma.MedComm · 2024Article
- Heterogeneity in tertiary lymphoid structures predicts distinct prognosis and immune microenvironmentJournal for immunotherapy of cancer · 2023Article
- Deciphering the implications of mitophagy-related signatures in clinical outcomes and microenvironment heterogeneity of clear cell renal cell carcinoma.Journal of cancer research and clinical oncology · 2023Article
- HK3 stimulates immune cell infiltration to promote glioma deterioration.Cancer cell international · 2023Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Wenhao XuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Wang-Rui LiuDepartment of Urology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, P.R. China.
Yue XuDepartment of Ophthalmology, Dushuhu Public Hospital Affiliated to Soochow University, Suzhou, 215000, P.R. China.
Xi TianDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Aihetaimujiang AnwaierDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Jia-Qi SuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Wen-Kai ZhuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Guo-Hai ShiDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Gao-Meng WeiDepartment of Urology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, P.R. China.
Yong-Ping HuangDepartment of Urology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, P.R. China.
Yuan-Yuan QuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Hai-Liang ZhangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Ding-Wei YeDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.
Fudan University Shanghai Cancer Center · CNAffiliated Hospital of Youjiang Medical University for Nationalities · CNSoochow University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Indexed as
Tumor MicroenvironmentBiomarkers, TumorCarcinogenesisCarcinoma, Renal CellFemaleGene Expression Regulation, NeoplasticGlycolysisHexokinaseHumansKidney NeoplasmsLymphocytes, Tumor-InfiltratingMacrophagesMaleMiddle AgedMonocytesPrognosisBiomarkers, TumorHexokinaseclear cell renal cell carcinomaglycolysisHK3immune checkpoint therapy (ICT)tumor microenvironment
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.