Evidence map›Paper›PMID 34238935›Full record

ReviewNature reviews. Disease primers2021

Psychopathy.

Stephane A De Brito, Adelle E Forth, Arielle R Baskin-Sommers, Inti A Brazil, Eva R Kimonis, Dustin Pardini, Paul J Frick, Robert James R Blair, Essi Viding

Erratum issuedOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 78 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 3 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 182 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Impact VR: Building Socioemotional Resilience in Youth with Conduct Disorder.Prevention science : the official journal of the Society for Prevention Research · 2026
    Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Psychopathic Traits and Sensation Seeking in Young General Population.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  15. Review
  16. Associations of brain structure with psychopathy.European archives of psychiatry and clinical neuroscience · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 5 countries.

Stephane A De BritoSchool of Psychology and Centre for Human Brain Health, University of Birmingham, Birmingham, UK. s.a.debrito@bham.ac.uk.ORCID http://orcid.org/0000-0002-9082-6185
Adelle E ForthDepartment of Psychology, Carleton University, Ottawa, Ontario, Canada.
Arielle R Baskin-SommersDepartment of Psychology, Yale University, New Haven, CT, USA.
Inti A BrazilRadboud University, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.
Eva R KimonisParent-Child Research Clinic, School of Psychology, University of New South Wales, Sydney, NSW, Australia.
Dustin PardiniDepartment of Criminology and Criminal Justice, Arizona State University, Phoenix, AZ, USA.
Paul J FrickDepartment of Psychology, Louisiana State University, Baton Rouge, LA, USA.
Robert James R BlairCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, USA.
Essi VidingDivision of Psychology and Language Sciences, University College London, London, UK. e.viding@ucl.ac.uk.
Arizona State University · USBoys Town · USCarleton University · CALouisiana State University · USRadboud University Nijmegen · NLThe London College · GBUniversity of Birmingham · GBUNSW Sydney · AUYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychopathy is a personality disorder characterized by a constellation of affective, interpersonal, lifestyle and antisocial features whose antecedents can be identified in a subgroup of young people showing severe antisocial behaviour. The prevalence of psychopathy in the general population is thought to be ~1%, but is up to 25% in prisoners. The aetiology of psychopathy is complex, with contributions of both genetic and environmental risk factors, and gene-environment interactions and correlations. Psychopathy is characterized by structural and functional brain abnormalities in cortical (such as the prefrontal and insular cortices) and subcortical (for example, the amygdala and striatum) regions leading to neurocognitive disruption in emotional responsiveness, reinforcement-based decision-making and attention. Although no effective treatment exists for adults with psychopathy, preliminary intervention studies targeting key neurocognitive disturbances have shown promising results. Given that psychopathy is often comorbid with other psychiatric disorders and increases the risk of physical health problems, educational and employment failure, accidents and criminality, the identification of children and young people at risk for this personality disorder and preventative work are important. Indeed, interventions that target the antecedents of psychopathic features in children and adolescents have been found to be effective.

Indexed as

Antisocial Personality DisorderAdolescentAdultChildHumans

Identifiers

PMID34238935
OpenAlexW4210950081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.