Evidence map›Paper›PMID 34238931›Full record

ArticleNPJ breast cancer2021

Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study.

John M S Bartlett, Jane Bayani, Elizabeth Kornaga, Keying Xu, Greg R Pond, Tammy Piper, Elizabeth Mallon, Cindy Q Yao, Paul C Boutros, Annette Hasenburg and 7 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Multi-omic Profiling of Recurrence Risk Across Breast Cancer Subtypes.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 6 countries.

John M S Bartlett *Diagnostic Development, Ontario Institute for Cancer Research, Toronto, ON, Canada. jbartlett@oicr.on.ca.ORCID http://orcid.org/0000-0002-0347-3888
Jane Bayani *Diagnostic Development, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Elizabeth Kornaga *Diagnostic Development, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Keying XuDiagnostic Development, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Greg R PondDepartment of Oncology, McMaster University, Kingston, ON, Canada.
Tammy PiperEdinburgh Cancer Research Centre, Edinburgh, UK.
Elizabeth MallonDepartment of Pathology, Glasgow, UK.
Cindy Q YaoInformatics & Computational Biology, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Paul C BoutrosInformatics & Computational Biology, Ontario Institute for Cancer Research, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-0553-7520
Annette HasenburgDept of Gynecology and Obstetrics, University Center Mainz, Mainz, Germany.
J A DunnUniversity of Warwick, Coventry, UK.
Christos MarkopoulosNational and Kapodistrian University of Athens, Medical School, Athens, Greece.
Luc DirixSt. Augustinus Hospital, Antwerp, Belgium.
Caroline SeynaeveErasmus MC Cancer Institute, Rotterdam, the Netherlands.
Cornelis J H van de VeldeLeiden University Medical Center, Leiden, the Netherlands.
Robert C SteinNational Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK.ORCID http://orcid.org/0000-0003-2969-0415
Daniel ReaCancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK.
Ontario Institute for Cancer Research · CACancer Research UK Clinical Trials Unit · GBEdinburgh Cancer Research · GBErasmus MC Cancer Institute · NLGlasgow Life · GBJohannes Gutenberg University Mainz · DELeiden University Medical Center · NLMcMaster University · CANational and Kapodistrian University of Athens · GRNational Institute for Health Research · GBUniversity of Warwick · GB

Funding

UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI David A. Nathanson · 2017 to 2026
$25.2M
NCI NIH HHS P50 CA211015
6 · The paper itself

Abstract

Multiparametric assays for risk stratification are widely used in the management of both node negative and node positive hormone receptor positive invasive breast cancer. Recent data from multiple sources suggests that different tests may provide different risk estimates at the individual patient level. The TEAM pathology study consists of 3284 postmenopausal ER+ve breast cancers treated with endocrine therapy Using genes comprising the following multi-parametric tests OncotypeDx

Identifiers

PMID34238931
PMCPMC8266887
OpenAlexW3180645260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.